{"id":"W2922377426","doi":"10.1097/aln.0000000000002655","title":"Extracellular Vesicles from Interferon-γ–primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli–induced Acute Lung Injury in Rats","year":2019,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Mesenchymal stem cell; Stromal cell; Extracellular; Medicine; Umbilical cord; Immunology; Cell biology; Biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002051045,0.0004838597,0.0003957336,0.000272692,0.00008989733,0.0002670741,0.0001845495,0.0003480152,0.001141302],"category_scores_gemma":[0.0001992688,0.0001509075,0.0003306665,0.00009894739,0.0002010486,0.000284503,0.0002066754,0.0005991591,0.0002621758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000145244,"about_ca_system_score_gemma":0.0002456942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002629824,"about_ca_topic_score_gemma":0.000363495,"domain_scores_codex":[0.9998761,0.00001844065,0.00001825897,0.00002123141,0.00002634333,0.00003959328],"domain_scores_gemma":[0.9998184,0.00001789562,0.00007722806,0.00001565301,0.0000218469,0.00004899117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001551967,0.000292112,0.0004531754,0.0000594097,0.0000151163,0.00004524525,0.00002573577,0.0001216017,0.9925155,0.00006937423,0.00004665844,0.00480405],"study_design_scores_gemma":[0.00007470198,0.004459624,0.003877486,0.00001511732,0.00003532221,0.00009689658,0.00005418533,0.0006232145,0.9900957,0.00004284782,0.000618954,0.000005992895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974326,0.0005631459,0.001329088,0.00005384363,0.00004592276,0.00003757777,0.0001192213,0.00004680042,0.0003717435],"genre_scores_gemma":[0.9958609,0.0006256609,0.001730594,0.00003916122,0.00001343139,0.00007010157,0.0002292434,0.00001307686,0.001417765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001141302,"threshold_uncertainty_score":0.003818035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01103486202741045,"score_gpt":0.2725777554178775,"score_spread":0.2615428933904671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}