{"id":"W2922397716","doi":"10.1101/573279","title":"Transcriptomic and Cellular Decoding of Regional Brain Vulnerability to Neurodevelopmental Disorders","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Neuroimaging; Neuroscience; Biology; Gene regulatory network; Transcriptome; Disease; Copy-number variation; Gene expression; Gene; Genetics; Medicine; Pathology; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002064099,0.0001650793,0.0001871605,0.0004809583,0.000129658,0.0004687685,0.0001388339,0.0002197641,0.001195724],"category_scores_gemma":[0.0003956636,0.00009998608,0.0001148589,0.000381309,0.0003168701,0.0001980425,0.0002380432,0.0002384373,0.0002436239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002584614,"about_ca_system_score_gemma":0.0001527485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001193988,"about_ca_topic_score_gemma":0.00140742,"domain_scores_codex":[0.9998928,0.00001623488,0.000005512395,0.00004399958,0.00002767238,0.00001376312],"domain_scores_gemma":[0.9998523,0.00005525832,0.00003529124,0.00002370015,0.00002075955,0.00001269774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009920878,0.00001013692,0.01093181,0.00002995541,0.00001704747,0.0001092614,0.00008067871,0.0009676216,0.9815637,0.001416127,0.0001539701,0.004620567],"study_design_scores_gemma":[0.00001492328,0.0001012088,0.3866518,0.00002356493,0.00005558486,0.0007424806,0.0006075829,0.02036579,0.5819242,0.005445523,0.004045277,0.00002215667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722148,0.0004793415,0.02252079,0.0001863807,0.00001622411,0.00001100861,0.002166567,0.0001501927,0.002254741],"genre_scores_gemma":[0.9903723,0.000241022,0.007533348,0.00003331693,0.000009945569,0.00001964472,0.0008759989,0.00002879361,0.000885651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001195724,"threshold_uncertainty_score":0.004000127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009545915702862362,"score_gpt":0.2043208620836065,"score_spread":0.1947749463807441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}