{"id":"W2922397716","doi":"10.1101/573279","title":"Transcriptomic and Cellular Decoding of Regional Brain Vulnerability to Neurodevelopmental Disorders","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Neuroimaging; Neuroscience; Biology; Gene regulatory network; Transcriptome; Disease; Copy-number variation; Gene expression; Gene; Genetics; Medicine; Pathology; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003142678,0.0003142302,0.0003175547,0.00009762036,0.00008454631,0.00004703665,0.0002883133,0.0002873702,0.00001660664],"category_scores_gemma":[0.00006460367,0.0003567758,0.0001119513,0.00009531154,0.00008753253,0.000006926035,0.0003436385,0.0002076536,0.000005231594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004868811,"about_ca_system_score_gemma":0.0003359591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004936419,"about_ca_topic_score_gemma":0.00001115962,"domain_scores_codex":[0.9983673,0.00009533194,0.0003875853,0.0007160585,0.0001513471,0.0002823522],"domain_scores_gemma":[0.9989568,0.00001935372,0.0001639307,0.0006041806,0.0001197674,0.0001359636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004196116,0.00005798377,0.02457213,0.0002401692,0.00007919654,8.989935e-7,0.0000293532,0.0002240223,0.9743252,0.0001762169,0.0002498971,0.000002934594],"study_design_scores_gemma":[0.0005900118,0.0001432047,0.1769173,0.0001046696,0.00005000558,3.643745e-8,0.00001983001,0.0001106292,0.8131428,0.000006185769,0.008222351,0.0006929883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950931,0.0004916717,0.002946994,0.0003780427,0.0003956979,0.0004640435,0.0001984878,0.00002256738,0.000009379628],"genre_scores_gemma":[0.9963863,0.0001227136,0.002978319,0.0002732211,0.0001144213,0.00005528277,0.000002850852,0.0000519587,0.00001489859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1611824,"threshold_uncertainty_score":0.9998884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009545915702862362,"score_gpt":0.2043208620836065,"score_spread":0.1947749463807441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}