{"id":"W2922408353","doi":"10.1002/jlb.2a0918-361r","title":"PGE2-induced migration of human brain endothelial cell is mediated though protein kinase A in cooperation of EP receptors","year":2019,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Grand Challenges Canada","keywords":"Prostaglandin E2 receptor; Angiogenesis; Biology; Receptor; Cell biology; Gene silencing; Prostaglandin E2; Agonist; Cell migration; Protein kinase A; G protein-coupled receptor; Signal transduction; Endothelial stem cell; Kinase; Endocrinology; Cancer research; Cell; Biochemistry; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001000063,0.0001469499,0.0006415476,0.0003705889,0.00001799096,0.00000315883,0.0001005571,0.0002606355,0.0002008778],"category_scores_gemma":[0.0003326517,0.0001105694,0.0001385121,0.0002099988,0.0000589819,0.00009420784,0.00001696903,0.0003149343,0.00001507972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001111425,"about_ca_system_score_gemma":0.0003354565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001269124,"about_ca_topic_score_gemma":0.00007336066,"domain_scores_codex":[0.9982312,0.0003302319,0.0009207502,0.0001397985,0.000193297,0.0001847733],"domain_scores_gemma":[0.9984217,0.0001609826,0.0008679131,0.0001595983,0.0003045699,0.00008520902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009358369,0.0001641146,0.02422789,0.0001742393,0.00003302053,0.0000202589,0.0008873593,0.00000354451,0.9726192,0.00007315138,0.0003589694,0.0005024414],"study_design_scores_gemma":[0.005119881,0.004467712,0.007458077,0.0002698858,0.00003064217,0.00002424809,0.0001094225,0.0001094197,0.9804951,0.00003042141,0.001788297,0.00009691395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982056,0.0001565017,0.00001763127,0.0004548893,0.0004131135,0.0005678262,0.000006673992,0.000005279421,0.000172467],"genre_scores_gemma":[0.9990859,0.00003640015,0.0001744653,0.0001761067,0.0002890065,0.00000614066,0.00002085667,0.00001593644,0.0001951816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01676982,"threshold_uncertainty_score":0.4508889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01346390401858197,"score_gpt":0.2796759066577748,"score_spread":0.2662120026391928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}