{"id":"W2922462872","doi":"10.1093/jcag/gwz006.049","title":"A50 MICROBIOTA-MAST CELL INTERACTIONS IN A HUMANIZED MOUSE MODEL OF IBS","year":2019,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Eosinophilic Esophagitis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; McMaster University","funders":"","keywords":"Tryptase; Degranulation; Histamine; Mast cell; Immunology; Histamine H4 receptor; Microbiology; Biology; Chemokine; Receptor; Inflammation; Pharmacology; Biochemistry; Histamine H2 receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000787224,0.001219954,0.0008429728,0.001326137,0.0005251164,0.0006443506,0.0004895364,0.001577738,0.003927734],"category_scores_gemma":[0.0002814149,0.0006335289,0.0009776237,0.0004721975,0.0007949235,0.0006774873,0.000480318,0.002255955,0.0009835983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004841046,"about_ca_system_score_gemma":0.000411279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004934606,"about_ca_topic_score_gemma":0.0007812112,"domain_scores_codex":[0.9991855,0.0001687233,0.00007853084,0.0002275885,0.000182937,0.0001567191],"domain_scores_gemma":[0.9995688,0.00003589761,0.0001268488,0.00007000189,0.00003469244,0.000163712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001965594,0.0009271229,0.0003396847,0.00009203946,0.00001980556,0.000296445,0.00006272548,0.00008972885,0.9944326,0.0001378762,0.0002502773,0.001385992],"study_design_scores_gemma":[0.002209254,0.02844231,0.02888413,0.0002007826,0.0002489384,0.005522011,0.0004727482,0.004610714,0.9124459,0.0007311392,0.01615275,0.00007916843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863498,0.003534041,0.004058762,0.0009387677,0.0002813766,0.0003252364,0.002402224,0.000348236,0.001761516],"genre_scores_gemma":[0.9751091,0.00286488,0.007579277,0.0006583238,0.00009772343,0.001106601,0.003089297,0.0000969181,0.00939784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003927734,"threshold_uncertainty_score":0.01313961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009807946559966318,"score_gpt":0.2283346058213119,"score_spread":0.2185266592613456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}