{"id":"W2922516295","doi":"10.1093/jcag/gwz006.010","title":"A11 THE INFLAMMATORY CASPASES COORDINATE MUCOSAL RESTRICTION OF SALMONELLA THROUGH THE EPITHELIAL-INTRINSIC INFLAMMASOME","year":2019,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia Hospital; University of British Columbia","funders":"","keywords":"Inflammasome; Salmonella enterica; Innate immune system; Microbiology; Caspase; Caspase 1; Pathogen; Salmonella; Inflammation; Biology; Cell biology; Chemistry; Immunology; Immune system; Apoptosis; Programmed cell death; Biochemistry; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001363237,0.0003875583,0.0002727828,0.0002642429,0.0001206249,0.0004635283,0.000154393,0.0004026313,0.002854537],"category_scores_gemma":[0.0001442586,0.000171537,0.0003065659,0.0001534277,0.0002892767,0.0003873856,0.0002380192,0.0009540398,0.0006886392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001822368,"about_ca_system_score_gemma":0.0001764205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002178707,"about_ca_topic_score_gemma":0.0002474397,"domain_scores_codex":[0.9997824,0.00003511762,0.00003437315,0.0000459886,0.00004551996,0.00005669986],"domain_scores_gemma":[0.9998184,0.00001419581,0.00006776001,0.00002176191,0.00003068111,0.00004717612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002838981,0.00002301372,0.0003328082,0.00005370211,0.000002622047,0.00004693792,0.00001313107,0.00002582675,0.9985408,0.00006340758,0.00004113108,0.0005727671],"study_design_scores_gemma":[0.00005370224,0.001100384,0.0278546,0.0000256736,0.00002678001,0.001349811,0.0001608024,0.0009168569,0.9647884,0.0002314133,0.003480928,0.0000105493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924282,0.002081479,0.002520338,0.0002140774,0.00005453013,0.00002810204,0.001055682,0.00008915296,0.00152827],"genre_scores_gemma":[0.9929793,0.00113155,0.00231589,0.00008023917,0.00001262911,0.0000355655,0.001142883,0.00001621244,0.002285593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002854537,"threshold_uncertainty_score":0.00954932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003877368188971065,"score_gpt":0.1937017555193586,"score_spread":0.1898243873303875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}