{"id":"W2922530643","doi":"10.1161/atvb.38.suppl_1.452","title":"Abstract 452: Estrogen Inhibits LDL Transcytosis by Coronary Artery Endothelial Cells via GPER and SR-BI","year":2018,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Transcytosis; GPER; Estrogen; Internal medicine; Endocrinology; Estrogen receptor; Endothelium; Chemistry; Biology; Receptor; Medicine; Endocytosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002114879,0.0003697835,0.0003394291,0.0001334437,0.0001634795,0.0002658711,0.0001784226,0.0003283209,0.003667467],"category_scores_gemma":[0.0001445423,0.0001469232,0.0003444128,0.0001655544,0.0001662474,0.0001752165,0.0001669008,0.0005477206,0.001084515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002100176,"about_ca_system_score_gemma":0.0002866386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003212552,"about_ca_topic_score_gemma":0.0005343604,"domain_scores_codex":[0.9998066,0.00003754104,0.00001851642,0.00004026344,0.0000553034,0.00004185251],"domain_scores_gemma":[0.9999278,0.00001559448,0.00001799661,0.00001066737,0.00001205013,0.00001591586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003302186,0.00005740528,0.0001263793,0.0001030489,0.00001335492,0.00003999165,0.00001561355,0.00002020089,0.9966952,0.00009821451,0.000209806,0.002290623],"study_design_scores_gemma":[0.000128857,0.00111281,0.008954216,0.00001703739,0.00004456154,0.0003570219,0.00002304147,0.0003679568,0.9820109,0.00006790211,0.006910224,0.000005472846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779284,0.009712429,0.004056273,0.000661289,0.0001606131,0.00006706353,0.001224843,0.000218489,0.005970603],"genre_scores_gemma":[0.9723634,0.003627514,0.003692871,0.0004065931,0.00006893601,0.0001170028,0.002173065,0.00005222236,0.01749836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003667467,"threshold_uncertainty_score":0.0122689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01311443531634258,"score_gpt":0.2359989817852077,"score_spread":0.2228845464688651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}