{"id":"W2922629816","doi":"10.1038/d41586-019-00802-w","title":"Ratcheting up lipopolysaccharide transport","year":2019,"lang":"en","type":"letter","venue":"Nature","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Lipopolysaccharide; Bacteria; Membrane; Glycolipid; Bacterial cell structure; Chemistry; Bacterial outer membrane; Cell membrane; Biophysics; Molecule; Cell biology; Microbiology; Biochemistry; Biology; Escherichia coli; Genetics; Organic chemistry; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001890014,0.0007094489,0.000735996,0.0004732742,0.00204685,0.002839173,0.0007971351,0.02096853,0.00583542],"category_scores_gemma":[0.009737355,0.000550671,0.0006056322,0.0003008612,0.002595389,0.001976502,0.001095799,0.01569196,0.00551418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003003837,"about_ca_system_score_gemma":0.001183897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00175759,"about_ca_topic_score_gemma":0.002721793,"domain_scores_codex":[0.9987424,0.0003021096,0.0001066793,0.0001701467,0.000465628,0.0002130654],"domain_scores_gemma":[0.9965847,0.001876708,0.0002251598,0.0002261752,0.0005663856,0.0005209225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004288637,0.00005200573,0.0004439016,0.000148792,0.00002795622,0.001986069,0.0000797157,0.0001844579,0.002867147,0.013032,0.9510598,0.02968941],"study_design_scores_gemma":[0.0002394658,0.0001290615,0.0009951319,0.0001517572,0.00003171649,0.001273242,0.0001453632,0.000989196,0.004198948,0.02540555,0.9663786,0.00006187335],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.001518404,0.007487214,0.0008884085,0.8789788,0.1017405,0.00002406581,0.00008452652,0.00009335465,0.009184652],"genre_scores_gemma":[0.03714319,0.008957226,0.001216945,0.7797679,0.1203038,0.0001322465,0.00008821292,0.00007072672,0.05231979],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.02096853,"threshold_uncertainty_score":0.02179444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006085099735913589,"score_gpt":0.2427370514184252,"score_spread":0.2366519516825116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}