{"id":"W2922671992","doi":"10.1161/atvbaha.119.312459","title":"AB023, A Novel Antibody That Binds Factor XI and Blocks Its Activation by Factor XIIa","year":2019,"lang":"en","type":"letter","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Thrombosis and Atherosclerosis Research Institute","funders":"","keywords":"Antibody; Factor (programming language); Chemistry; Factor XII; Cell biology; Internal medicine; Endocrinology; Biology; Medicine; Immunology; Computer science; Coagulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008163595,0.0006642365,0.0007252283,0.0004624213,0.001304672,0.001374667,0.0007618371,0.01891211,0.00221714],"category_scores_gemma":[0.005605436,0.0003919466,0.0006793316,0.000279579,0.001191849,0.001285968,0.0003702941,0.01039692,0.001921543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002654046,"about_ca_system_score_gemma":0.001382095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003073752,"about_ca_topic_score_gemma":0.003082171,"domain_scores_codex":[0.9992278,0.0002098541,0.00009487385,0.000101918,0.0001983628,0.0001673471],"domain_scores_gemma":[0.9988598,0.0007230165,0.00008276407,0.00003292928,0.0001392977,0.0001621816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00085244,0.0005596029,0.005319541,0.0003233323,0.00009291655,0.195805,0.0003195391,0.0004492039,0.006321152,0.0105086,0.7287793,0.05066933],"study_design_scores_gemma":[0.002451707,0.001127285,0.009775115,0.0004183696,0.0002077241,0.1482897,0.0003386155,0.004368378,0.004155735,0.01473238,0.814016,0.0001188692],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.01775008,0.005148833,0.001205034,0.9130621,0.03784219,0.0001366739,0.0001700888,0.0001091571,0.02457587],"genre_scores_gemma":[0.1422297,0.008918714,0.002008091,0.6701241,0.1288282,0.0002699263,0.0002639334,0.00007514235,0.0472822],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01891211,"threshold_uncertainty_score":0.01925653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06012744814916085,"score_gpt":0.3027680099360365,"score_spread":0.2426405617868756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}