{"id":"W2922708500","doi":"10.1038/s41598-019-38736-y","title":"Oncosuppressor-Mutated Cells as a Liquid Biopsy Test for Cancer-Screening","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Cancer; Biopsy; Liquid biopsy; Cancer cell; PTEN; Immunohistochemistry; Cancer research; Pathology; Dysplasia; Medicine; Biology; Internal medicine; Cell biology; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003928685,0.0001516322,0.0001593105,0.00005695795,0.000148236,0.0001534362,0.0001552748,0.0001120043,0.0001146118],"category_scores_gemma":[0.0002000297,0.0001506585,0.0001280907,0.0001473285,0.00009201081,0.000005070191,0.0001244041,0.00005221241,0.00002674661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002498632,"about_ca_system_score_gemma":0.0003174103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001242612,"about_ca_topic_score_gemma":0.00005985196,"domain_scores_codex":[0.9983645,0.000009540965,0.0003170583,0.000787363,0.0001793088,0.0003422236],"domain_scores_gemma":[0.99866,0.00003940021,0.0002202586,0.000731857,0.0002228332,0.0001256445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006790658,0.00004579051,0.001562337,0.00002290601,0.00002399001,0.00002670626,0.00003764881,0.0007323882,0.9757641,0.0000106448,0.02103825,0.000667317],"study_design_scores_gemma":[0.0002053969,0.0002096274,0.00006624175,0.00001823784,0.00001603798,0.00005354201,0.00002784647,0.0001351962,0.6448154,0.0001440975,0.354148,0.0001603685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905525,0.000632169,0.000735164,0.0001371623,0.005895983,0.0006057878,0.00009056927,0.0000194657,0.001331156],"genre_scores_gemma":[0.9875547,0.00004740502,0.0013065,0.0001475689,0.0002684988,0.0001000827,0.0003983888,0.00003460481,0.01014224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3331098,"threshold_uncertainty_score":0.6143677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009654410725190295,"score_gpt":0.262721530725654,"score_spread":0.2530671200004637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}