{"id":"W2922708500","doi":"10.1038/s41598-019-38736-y","title":"Oncosuppressor-Mutated Cells as a Liquid Biopsy Test for Cancer-Screening","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Cancer; Biopsy; Liquid biopsy; Cancer cell; PTEN; Immunohistochemistry; Cancer research; Pathology; Dysplasia; Medicine; Biology; Internal medicine; Cell biology; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003945989,0.0004165302,0.0002466454,0.0005536081,0.0001428128,0.0003269528,0.0002726057,0.0004573458,0.000996565],"category_scores_gemma":[0.0003773581,0.0001400973,0.0001978134,0.0002417965,0.0002980343,0.0002544558,0.0003743155,0.0005218628,0.0003700587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001672761,"about_ca_system_score_gemma":0.0001459316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003585631,"about_ca_topic_score_gemma":0.0005598374,"domain_scores_codex":[0.9995943,0.0001328946,0.00001655379,0.00005656908,0.0001548473,0.00004490373],"domain_scores_gemma":[0.9997402,0.0001011447,0.00004763871,0.00003220422,0.00003950684,0.00003937399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007918471,0.00003144825,0.001582538,0.00002795766,0.000005994252,0.00008621747,0.00002028121,0.00007808534,0.9941087,0.0001347977,0.00004288012,0.003801974],"study_design_scores_gemma":[0.000005207032,0.0003748547,0.002677888,0.000004101134,0.0000179082,0.0004516784,0.00002583586,0.001394423,0.9934737,0.00009349648,0.001474093,0.000006840065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9128539,0.003322212,0.07887312,0.0002516862,0.0001099509,0.0002220106,0.0005124991,0.0006581764,0.003196424],"genre_scores_gemma":[0.9589042,0.001010646,0.03682495,0.00017799,0.00002206108,0.0001015243,0.0004979434,0.0000363404,0.002424457],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000996565,"threshold_uncertainty_score":0.003333807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009654410725190295,"score_gpt":0.262721530725654,"score_spread":0.2530671200004637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}