{"id":"W2923075919","doi":"10.1016/bs.irn.2019.03.001","title":"Dysfunction of mitochondria: Implications for Alzheimer's disease","year":2019,"lang":"en","type":"review","venue":"International review of neurobiology","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Mitochondrion; Disease; Neuroscience; Tau protein; Dementia; Alzheimer's disease; Acetylcholine; Amyloid (mycology); Bioenergetics; Neurotransmitter; Biology; Medicine; Psychology; Bioinformatics; Internal medicine; Pharmacology; Cell biology; Pathology; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006971333,0.001087999,0.001823227,0.00216936,0.0003516652,0.001547678,0.001098105,0.001665682,0.003884805],"category_scores_gemma":[0.0008449716,0.0002449434,0.0004945287,0.002936786,0.0006580825,0.001642386,0.001022074,0.001998353,0.002037504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008133251,"about_ca_system_score_gemma":0.001761338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00140082,"about_ca_topic_score_gemma":0.002950673,"domain_scores_codex":[0.9998111,0.00003316048,0.00003068499,0.00004065678,0.00006387784,0.00002061018],"domain_scores_gemma":[0.9995688,0.0001701559,0.0000956504,0.00001104422,0.0001072832,0.00004715408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001362595,0.00008186781,0.0002441989,0.02417197,0.0001302058,0.000193319,0.00005276611,0.0002758781,0.001999159,0.004265917,0.03900841,0.92944],"study_design_scores_gemma":[0.00005061237,0.0001383653,0.001173287,0.007827456,0.0002891827,0.001172371,0.0001208935,0.0001009202,0.0003639617,0.005906825,0.9828238,0.00003220218],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000317519,0.9992311,0.00004927718,0.0002599965,0.0001469354,0.000001720878,0.00001090947,0.00000355839,0.0002647856],"genre_scores_gemma":[0.0002588566,0.9992449,0.00007676936,0.0001439787,0.0001374359,0.000002289013,0.00001247715,3.878549e-7,0.0001229767],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003884805,"threshold_uncertainty_score":0.0129959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1187649269592783,"score_gpt":0.4408921828390738,"score_spread":0.3221272558797955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}