{"id":"W2923290218","doi":"10.1523/eneuro.0086-19.2019","title":"The Expression of Key Guidance Genes at a Forebrain Axon Turning Point Is Maintained by Distinct Fgfr Isoforms but a Common Downstream Signal Transduction Mechanism","year":2019,"lang":"en","type":"article","venue":"eNeuro","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates - Health Solutions; Government of Canada","keywords":"Axon guidance; Biology; Forebrain; Neuroscience; Fibroblast growth factor; FGF8; Semaphorin; Cell biology; Growth cone; Signal transduction; Neural development; Axon; Genetics; Receptor; Gene; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001014062,0.000372559,0.0002084647,0.0002574862,0.000152764,0.0002618855,0.0001778187,0.0002663697,0.0007329031],"category_scores_gemma":[0.00009732343,0.0002117553,0.0003206762,0.0000981797,0.0002429413,0.0001508856,0.00023076,0.0004211648,0.0003475448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005411681,"about_ca_system_score_gemma":0.0002767876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001041413,"about_ca_topic_score_gemma":0.001527924,"domain_scores_codex":[0.9998116,0.00001095431,0.00001486084,0.0000458282,0.00005596246,0.00006071118],"domain_scores_gemma":[0.9998345,0.00001549866,0.00006336791,0.0000160337,0.00002406243,0.00004637655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001256221,0.000001273418,0.0001386703,0.000004890728,8.959138e-7,0.00001726899,0.000003035987,0.00001148491,0.9995816,0.00003692411,0.000004065688,0.0001873408],"study_design_scores_gemma":[0.000008207834,0.0001205388,0.03144839,0.000007303408,0.00001394245,0.0003916388,0.00003607082,0.0006323133,0.9663454,0.00006295052,0.0009282565,0.000004982487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953465,0.0007455716,0.00209343,0.00005789305,0.00001163055,0.00001281189,0.0002899128,0.00006452502,0.001377856],"genre_scores_gemma":[0.9957215,0.0003029482,0.001523698,0.00003092453,0.000004959116,0.00001964187,0.0004258078,0.00001613707,0.00195434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001041413,"threshold_uncertainty_score":0.003926456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01255462750668078,"score_gpt":0.2309476129413086,"score_spread":0.2183929854346278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}