{"id":"W2923524419","doi":"10.1101/585653","title":"ZBTB33 (Kaiso) methylated binding sites are associated with primed heterochromatin","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Cancer Science Institute of Singapore, National University of Singapore; Ministry of Education, India; National Research Foundation Singapore; National Medical Research Council; Medical Research Council; National Research Foundation","keywords":"Histone; Heterochromatin; Chromatin; Epigenetics; DNA methylation; Epigenomics; Biology; Genetics; Methylated DNA immunoprecipitation; DNA; Computational biology; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009225805,0.0001674519,0.000157733,0.0003336231,0.0001636909,0.0002838834,0.0001749384,0.0002064404,0.003360093],"category_scores_gemma":[0.0001550013,0.0001835527,0.0002294034,0.0003298601,0.0001804128,0.0001369399,0.0002687394,0.0003101022,0.0006658968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00026735,"about_ca_system_score_gemma":0.0001135995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001278743,"about_ca_topic_score_gemma":0.001834854,"domain_scores_codex":[0.9998825,0.00000740953,0.00000433139,0.00005301055,0.00002738922,0.00002535912],"domain_scores_gemma":[0.999845,0.00002123585,0.0000712243,0.00001393388,0.0000188311,0.00002971345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001398426,0.000006409392,0.004567968,0.00008106307,0.00002157146,0.00005293238,0.00002822497,0.0002022319,0.9920849,0.0002001373,0.0001594233,0.002455324],"study_design_scores_gemma":[0.00002676484,0.0001333649,0.3278605,0.0000317911,0.00009068334,0.0007315824,0.0001409474,0.005636286,0.6557854,0.000752582,0.008785337,0.00002475582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838344,0.001652178,0.01056568,0.00005769169,0.0000170207,0.00001677762,0.00185301,0.0003901646,0.001613114],"genre_scores_gemma":[0.9957722,0.0001815821,0.00148141,0.00004309578,0.00000316967,0.00001084789,0.001221225,0.00003667337,0.001249773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003360093,"threshold_uncertainty_score":0.0112406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01418217797437134,"score_gpt":0.2261796871121936,"score_spread":0.2119975091378223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}