{"id":"W2923543767","doi":"10.1126/science.aav2914","title":"Autologous grafting of cryopreserved prepubertal rhesus testis produces sperm and offspring","year":2019,"lang":"en","type":"article","venue":"Science","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":327,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health","keywords":"Cryopreservation; Andrology; Spermatogenesis; Sperm; Offspring; Testosterone (patch); Testicular sperm extraction; Fertility; Biology; Fertility preservation; Pregnancy; Embryo; Medicine; Physiology; Infertility; Intracytoplasmic sperm injection; Endocrinology; Population","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001662606,0.0001767347,0.0001520807,0.0001895339,0.0002294391,0.0001973694,0.0002128114,0.0001786041,0.003577177],"category_scores_gemma":[0.0001567985,0.00006835635,0.0001446571,0.0000753386,0.000226933,0.0001477215,0.0001989223,0.0003368603,0.0005323444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000998048,"about_ca_system_score_gemma":0.0002007963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003668178,"about_ca_topic_score_gemma":0.0007991563,"domain_scores_codex":[0.9999417,0.0000107347,0.000005141662,0.00001478071,0.00001647745,0.00001119118],"domain_scores_gemma":[0.999831,0.00003207859,0.00004071202,0.00004164109,0.0000192012,0.00003538177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001342461,0.00005176344,0.001497838,0.00005213068,0.000009146571,0.0004459796,0.0001268547,0.00006369088,0.9897677,0.0005422969,0.0001055351,0.007202707],"study_design_scores_gemma":[0.00001911936,0.001627146,0.01803221,0.00002958552,0.00004595405,0.003704921,0.0002302384,0.0006099707,0.9621978,0.0002394114,0.01325342,0.00001014193],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909222,0.002010777,0.003294224,0.00006920376,0.00005668904,0.00005510033,0.000204199,0.00006343461,0.003324164],"genre_scores_gemma":[0.9906272,0.001323316,0.002832022,0.0000544427,0.0000247047,0.00003651149,0.0003132513,0.00003145017,0.004757248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003577177,"threshold_uncertainty_score":0.01196682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01490147457360596,"score_gpt":0.2566040129677144,"score_spread":0.2417025383941084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}