{"id":"W2923803773","doi":"10.3389/fnagi.2019.00047","title":"Pathological Changes in Microvascular Morphology, Density, Size and Responses Following Comorbid Cerebral Injury","year":2019,"lang":"en","type":"article","venue":"Frontiers in Aging Neuroscience","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Ischemia; Pathology; Neuroinflammation; Microcirculation; Blood–brain barrier; Medicine; Vascular permeability; Occludin; Pathological; Brain ischemia; Neuroscience; Biology; Tight junction; Central nervous system; Disease; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001105822,0.0001581739,0.0002471285,0.0003722675,0.0001455836,0.0002047543,0.0001308594,0.0001888241,0.0008176839],"category_scores_gemma":[0.0002256129,0.00007334158,0.0001042139,0.0002287355,0.0001856235,0.0002330574,0.0001841219,0.000289028,0.00007579178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002190568,"about_ca_system_score_gemma":0.0001534146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007702645,"about_ca_topic_score_gemma":0.001206728,"domain_scores_codex":[0.9999336,0.000008313867,0.000004330009,0.00002080234,0.00001542959,0.00001762185],"domain_scores_gemma":[0.999871,0.000009956759,0.00007256456,0.000008771503,0.00001511584,0.00002247911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00226853,0.0003202916,0.09174485,0.0002515689,0.0001577642,0.003347472,0.0003770953,0.0004391145,0.855421,0.0007624574,0.0003606275,0.04454926],"study_design_scores_gemma":[0.00001382936,0.001556516,0.870215,0.00002799966,0.0001049693,0.004843205,0.0004549787,0.0008472491,0.1197713,0.0008853897,0.001262027,0.00001753274],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971247,0.0008904997,0.001208046,0.00003115878,0.000008075572,0.0000132769,0.0001312739,0.000019231,0.0005737902],"genre_scores_gemma":[0.9976639,0.001078694,0.0005453117,0.00002046047,0.00001038567,0.00002004146,0.000134703,0.000003418779,0.0005231641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008176839,"threshold_uncertainty_score":0.002735436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01969782097453166,"score_gpt":0.2577543384260002,"score_spread":0.2380565174514686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}