{"id":"W2923908603","doi":"10.3389/fimmu.2019.00522","title":"Pleiotropic Effects of IL-33 on CD4+ T Cell Differentiation and Effector Functions","year":2019,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"GATA3; FOXP3; Cell biology; Innate lymphoid cell; IL-2 receptor; Immunology; Immune system; T cell; Interleukin 33; Biology; Interleukin 21; Antigen-presenting cell; Cytokine; Receptor; Innate immune system; Interleukin; Transcription factor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001532261,0.0006465073,0.002708686,0.000906908,0.0001277022,0.00001145806,0.0003970017,0.001669794,0.00004926358],"category_scores_gemma":[0.00018094,0.0005533434,0.000376043,0.0003335385,0.0003854265,0.0000684903,0.0001767268,0.001204761,0.0007217606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001961942,"about_ca_system_score_gemma":0.0002043788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004902973,"about_ca_topic_score_gemma":0.000008906031,"domain_scores_codex":[0.9967062,0.001125168,0.00077295,0.0007216277,0.0000503497,0.0006236441],"domain_scores_gemma":[0.9979607,0.0006491898,0.0005957804,0.0007204859,0.00005145272,0.00002234851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004062002,0.00093884,0.001132602,0.04401217,0.002932377,0.0000228035,0.0005541215,0.000001408069,0.007372059,0.000436007,0.02690013,0.9152913],"study_design_scores_gemma":[0.00219552,0.00125535,0.001253844,0.003300379,0.0009156486,0.00002867853,0.00004692182,8.058569e-7,0.0009302894,0.00004336466,0.9895446,0.0004846457],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005433821,0.9748442,0.0005380012,0.000004415161,0.01481032,0.001455013,0.002234692,0.00005901167,0.0006205123],"genre_scores_gemma":[0.002320789,0.9919215,0.00007775063,0.0000190762,0.00006528155,0.000193813,0.001778424,0.00007230811,0.003551082],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9626444,"threshold_uncertainty_score":0.9996918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01038351878058235,"score_gpt":0.2227393767449134,"score_spread":0.212355857964331,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}