{"id":"W2924087040","doi":"10.1016/j.mrgentox.2019.02.004","title":"Chemically induced aneuploidy in germ cells. Part II of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases","year":2019,"lang":"en","type":"article","venue":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Aneuploidy; Biology; Germ cell; Somatic cell; Genetics; Meiosis; Oocyte; Immunology; Cancer research; Chromosome; Embryo; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001139287,0.0005142218,0.0002846192,0.002571749,0.0005378402,0.0004407018,0.0004774056,0.0009533328,0.002479564],"category_scores_gemma":[0.0008750231,0.0001800141,0.0005700595,0.0009705755,0.0006075256,0.0002392492,0.0007600236,0.0006340336,0.0004871615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009865044,"about_ca_system_score_gemma":0.001034791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003436095,"about_ca_topic_score_gemma":0.004051868,"domain_scores_codex":[0.9991278,0.0002990617,0.0000756365,0.0001003233,0.0003103638,0.00008680819],"domain_scores_gemma":[0.9990687,0.0002951007,0.0002239363,0.0001256442,0.0001838936,0.0001028017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007374358,0.0003574658,0.0210891,0.001035151,0.0002096449,0.0007323941,0.0002172673,0.001400527,0.902959,0.00281062,0.008172344,0.06027893],"study_design_scores_gemma":[0.00004456395,0.00125811,0.09239415,0.0001677989,0.000171842,0.0008955057,0.0001815091,0.0003212018,0.8520041,0.001105485,0.05141612,0.0000395825],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8124115,0.07563423,0.01901392,0.004432928,0.002814455,0.001832564,0.01505881,0.0003741478,0.06842747],"genre_scores_gemma":[0.8669541,0.05903112,0.006355946,0.002034557,0.0005824104,0.0008205443,0.01046438,0.0001657315,0.05359116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003436095,"threshold_uncertainty_score":0.00829494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01495083186673971,"score_gpt":0.2734260904042986,"score_spread":0.2584752585375589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}