{"id":"W2924119339","doi":"10.1016/j.cell.2019.01.033","title":"Global Genetic Networks and the Genotype-to-Phenotype Relationship","year":2019,"lang":"en","type":"review","venue":"Cell","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":260,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto; McGill University Health Centre; St. Michael's Hospital","funders":"National Human Genome Research Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Phenotype; Genetics; Allele; Gene; Genome; Genotype-phenotype distinction; Computational biology; Evolutionary biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002315551,0.0002692213,0.0004729939,0.00003032707,0.00009940017,0.0000611301,0.0004229578,0.0003776808,0.00002003942],"category_scores_gemma":[0.00006755339,0.000174281,0.0002030594,0.0002128337,0.0001221943,7.068969e-7,0.0004337051,0.0002207806,0.0002932177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002177949,"about_ca_system_score_gemma":0.0001966504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009243939,"about_ca_topic_score_gemma":0.000009055926,"domain_scores_codex":[0.9985501,0.0002382924,0.0002643616,0.0004732142,0.0001521027,0.0003219536],"domain_scores_gemma":[0.9990066,0.00007431197,0.00008829193,0.0006337748,0.00006010631,0.0001369581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002624683,0.00008205681,0.0004757081,0.008570846,0.0003244067,0.00001110815,0.00003147329,0.002002243,0.00006439094,0.0009166986,0.01500159,0.972257],"study_design_scores_gemma":[0.0003264108,0.00008953168,0.0001855124,0.0001982225,0.0002086543,0.00001480433,0.000002692056,0.00006944401,0.000005888308,0.00007806067,0.9985769,0.0002439257],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000177057,0.991887,0.0007436922,0.00002215621,0.0002609252,0.0008418182,0.00003302728,0.000005796105,0.006028468],"genre_scores_gemma":[0.00226771,0.9921923,0.0002085679,0.0001133033,0.000492137,0.00005964445,0.0001404967,0.00004025223,0.004485616],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9835753,"threshold_uncertainty_score":0.7106971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0327936820214391,"score_gpt":0.3127825330961077,"score_spread":0.2799888510746685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}