{"id":"W2924418428","doi":"10.1101/575415","title":"Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen <i>Citrobacter rodentium</i>","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"CH.I.L.D. Foundation","keywords":"Citrobacter rodentium; Lamina propria; Biology; Inflammation; Pathogen; Microbiology; Immunity; Immune system; Immunology; Intracellular parasite; Intestinal mucosa; Medicine; Epithelium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002113835,0.0006556938,0.0002841349,0.0005851181,0.0002073405,0.0002894014,0.0003398577,0.000660477,0.001935934],"category_scores_gemma":[0.000199958,0.0002941369,0.0002588298,0.0001722448,0.0004667944,0.0001874019,0.0003933436,0.0008386109,0.0004597639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004317955,"about_ca_system_score_gemma":0.0001739195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005890726,"about_ca_topic_score_gemma":0.000757425,"domain_scores_codex":[0.9996974,0.00005907925,0.00004214049,0.00008193742,0.0000508728,0.00006849196],"domain_scores_gemma":[0.9994252,0.00005405126,0.0002625641,0.00004235086,0.00002424664,0.0001915688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000217602,0.00003433081,0.0003792002,0.00003308007,0.00000428131,0.0001509248,0.00001603185,0.00005609471,0.99857,0.00005540382,0.00002842728,0.0004546567],"study_design_scores_gemma":[0.00008310482,0.0008039857,0.03389778,0.00004439585,0.00003519121,0.003640817,0.0002011265,0.001715157,0.9567152,0.0001279506,0.002714801,0.00002037037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969565,0.0005779192,0.001104905,0.0001148977,0.00001786285,0.00002581872,0.0005379717,0.0001010516,0.0005630381],"genre_scores_gemma":[0.9967457,0.0001858605,0.001353243,0.00005986878,0.000005900688,0.0000286081,0.0003573596,0.00003590834,0.001227525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001935934,"threshold_uncertainty_score":0.006476343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008714876288618202,"score_gpt":0.2060868681543722,"score_spread":0.197371991865754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}