{"id":"W2924513772","doi":"10.1002/jbmr.3698","title":"Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry","year":2019,"lang":"en","type":"review","venue":"Journal of Bone and Mineral Research","topic":"Bone health and osteoporosis research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Research Resources; National Center for Advancing Translational Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; National Human Genome Research Institute; Novo Nordisk Fonden; Wellcome Trust","keywords":"Femoral neck; Genome-wide association study; Hip bone; Hip fracture; Meta-analysis; Medicine; Femur; Biology; Single-nucleotide polymorphism; Bone mineral; Internal medicine; Genetics; Osteoporosis; Gene; Genotype; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01228309,0.002180413,0.005757088,0.004494247,0.000729995,0.00314033,0.001772991,0.001568291,0.00255173],"category_scores_gemma":[0.01793141,0.0011941,0.02302215,0.008159077,0.0005654171,0.0008837618,0.001457743,0.001979667,0.0002664347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006337168,"about_ca_system_score_gemma":0.0007816126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003815637,"about_ca_topic_score_gemma":0.005736689,"domain_scores_codex":[0.9905187,0.005094456,0.001200027,0.002042977,0.0008057499,0.0003380472],"domain_scores_gemma":[0.9846326,0.01058454,0.00153794,0.002390096,0.0005630734,0.0002917128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0035652,0.00004457846,0.2667668,0.003922627,0.7078152,0.0006495994,0.00007991337,0.003152174,0.0030869,0.000393047,0.001253825,0.009270069],"study_design_scores_gemma":[0.0007786117,0.0004683699,0.2137385,0.0007595003,0.7722444,0.000721,0.0001204753,0.005788519,0.001389049,0.001712888,0.002224127,0.00005454422],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5041876,0.45356,0.02830352,0.002432443,0.00108569,0.0001996342,0.007686604,0.0008074362,0.001737136],"genre_scores_gemma":[0.9770426,0.01656524,0.00405722,0.0003316058,0.0002244284,0.0001015408,0.001351839,0.00009133424,0.0002342703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01228309,"threshold_uncertainty_score":0.06496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5061408923288553,"score_gpt":0.5367154110630639,"score_spread":0.03057451873420858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}