{"id":"W2924791861","doi":"10.1007/s13300-019-0594-6","title":"Downregulation of T-Cell Transcription Factors in Adult Latent Autoimmune Diabetes with High-Titer Glutamic Acid Decaroxylase Antibody","year":2019,"lang":"en","type":"article","venue":"Diabetes Therapy","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Education and Child Care","funders":"National Key Research and Development Program of China","keywords":"FOXP3; GATA3; RAR-related orphan receptor gamma; Medicine; Immunology; Peripheral blood mononuclear cell; Titer; Antibody; T cell; Internal medicine; T helper cell; Endocrinology; Diabetes mellitus; Flow cytometry; Transcription factor; Immune system; Biology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001613708,0.0002038868,0.0001989692,0.0001800211,0.0001145996,0.0001848473,0.00007697342,0.0001496063,0.000976389],"category_scores_gemma":[0.0002260306,0.00007929705,0.0001321322,0.0001579181,0.0001730346,0.000127467,0.0001402042,0.0002377912,0.0001742616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001082891,"about_ca_system_score_gemma":0.00007946056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001716444,"about_ca_topic_score_gemma":0.0001705955,"domain_scores_codex":[0.9999046,0.00002404001,0.00001133863,0.00002096217,0.00001687912,0.00002215656],"domain_scores_gemma":[0.9998686,0.00002115437,0.00005204101,0.000008269661,0.00001484929,0.00003498776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00468428,0.0002913165,0.1953163,0.0002383502,0.00005555093,0.001502673,0.0003535424,0.0000699768,0.7815589,0.00006615787,0.0001642979,0.01569885],"study_design_scores_gemma":[0.0002330509,0.00264885,0.938714,0.00003696009,0.0001291973,0.005183672,0.0004489362,0.001003437,0.04971465,0.0001132219,0.001764319,0.000009755956],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990323,0.0006194506,0.0001528451,0.0000116177,0.000004513177,0.000003136471,0.000024814,0.000005763244,0.0001455818],"genre_scores_gemma":[0.9994512,0.0001893401,0.0001391929,0.00002210195,0.00001122915,0.000007415763,0.00005767369,0.000001245927,0.000120722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000976389,"threshold_uncertainty_score":0.003266335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003260832056153989,"score_gpt":0.1953484227503229,"score_spread":0.1920875906941689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}