{"id":"W2924791861","doi":"10.1007/s13300-019-0594-6","title":"Downregulation of T-Cell Transcription Factors in Adult Latent Autoimmune Diabetes with High-Titer Glutamic Acid Decaroxylase Antibody","year":2019,"lang":"en","type":"article","venue":"Diabetes Therapy","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Education and Child Care","funders":"National Key Research and Development Program of China","keywords":"FOXP3; GATA3; RAR-related orphan receptor gamma; Medicine; Immunology; Peripheral blood mononuclear cell; Titer; Antibody; T cell; Internal medicine; T helper cell; Endocrinology; Diabetes mellitus; Flow cytometry; Transcription factor; Immune system; Biology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001236777,0.0002521223,0.0003173056,0.000106553,0.00002940261,0.00002401667,0.0001696755,0.0001892615,0.00004869441],"category_scores_gemma":[0.000006740547,0.0002037424,0.0001268953,0.0001973336,0.00005925729,0.0000200167,0.00001816951,0.00009294693,0.000007519737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002024684,"about_ca_system_score_gemma":0.00003124935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003063893,"about_ca_topic_score_gemma":0.00001556428,"domain_scores_codex":[0.998712,0.00007523654,0.0002906434,0.0003525929,0.0001732391,0.0003963108],"domain_scores_gemma":[0.9993659,0.00001504884,0.0001653335,0.0003131012,0.000096149,0.00004446098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003846686,0.0001603458,0.3994752,0.00002362907,0.00006191547,8.943122e-8,0.00008332341,0.0002066853,0.5990962,0.000009370468,0.000007005391,0.0008376564],"study_design_scores_gemma":[0.001916722,0.0005058236,0.3844469,0.00004104787,0.00001117606,1.494468e-8,0.00004511588,0.0001590746,0.6125468,0.00002910659,0.0001075687,0.0001907049],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982299,0.001069848,0.00001290572,0.00005195964,0.0001046622,0.0003915081,0.0000398562,0.00001983703,0.00007951277],"genre_scores_gemma":[0.9982482,0.000417827,0.00007252972,0.0001441973,0.00002095336,0.00002013961,0.0009290099,0.0000421657,0.0001050111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01502838,"threshold_uncertainty_score":0.8308372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003260832056153989,"score_gpt":0.1953484227503229,"score_spread":0.1920875906941689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}