{"id":"W2924859841","doi":"10.1096/fj.201900146r","title":"Artesunate prevents type 1 diabetes in NOD mice mainly by inducing protective IL‐4—producing T cells and regulatory T cells","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Education and Child Care","funders":"Graduate Innovation Project of North Minzu University; National Natural Science Foundation of China; National Outstanding Youth Science Fund Project of National Natural Science Foundation of China; National Institutes of Health; Central South University; National Institutes of Natural Sciences","keywords":"NOD mice; Nod; Type 1 diabetes; Artesunate; Immune system; Immunology; Spleen; Proinflammatory cytokine; Medicine; CD8; Diabetes mellitus; Pharmacology; Endocrinology; Inflammation; Malaria; Plasmodium falciparum","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007752125,0.0001466176,0.0001888811,0.0001105505,0.0002074643,0.00004116018,0.0001417023,0.0001329894,0.0005841805],"category_scores_gemma":[0.00003570423,0.0001077828,0.00004745523,0.0001157317,0.00006544175,0.0002175867,0.00005582762,0.0008971199,0.0004741794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008834541,"about_ca_system_score_gemma":0.00004299188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003691965,"about_ca_topic_score_gemma":0.00000317271,"domain_scores_codex":[0.9987765,0.0003827715,0.0002752253,0.0002186553,0.0000441252,0.0003027021],"domain_scores_gemma":[0.9994162,0.00009652662,0.000214314,0.0001900702,0.00006255874,0.00002034589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001409177,0.00004975874,0.001447881,0.00001199619,0.00007430718,0.00000102652,0.0008373311,0.00002789854,0.9930013,0.000003642988,0.003562197,0.0008416733],"study_design_scores_gemma":[0.000823943,0.0002099722,0.003650002,0.0001203293,0.00002128073,0.00006622259,0.0005944409,0.00003541831,0.9911829,0.00005879999,0.003103639,0.0001330728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944893,0.001043384,0.00001264727,0.0001210761,0.003644193,0.0003157713,0.000003625476,0.00001554723,0.0003544349],"genre_scores_gemma":[0.989803,0.00007997562,0.00001465965,0.0002224975,0.00004711102,0.000004671171,0.000007813547,0.00001686422,0.009803436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009449,"threshold_uncertainty_score":0.6396368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006463677863323432,"score_gpt":0.1982541642840882,"score_spread":0.1917904864207648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}