{"id":"W2924871266","doi":"10.1016/j.coi.2019.02.004","title":"Mitochondrial antigen presentation: a mechanism linking Parkinson’s disease to autoimmunity","year":2019,"lang":"en","type":"review","venue":"Current Opinion in Immunology","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Parkinson Canada","keywords":"Autoimmunity; Neuroinflammation; Disease; Immunology; Mechanism (biology); Neuroscience; Parkinson's disease; Immune system; Antigen presentation; Medicine; Autoimmune disease; T cell; Biology; Inflammation; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001818404,0.0007778197,0.002323214,0.001007415,0.0001359644,0.00005781859,0.0004963379,0.0004712428,0.0002390266],"category_scores_gemma":[0.0001630803,0.0006973493,0.0007559465,0.0006661311,0.00006551222,0.0001119393,0.0004511358,0.0009548324,0.001198149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006013226,"about_ca_system_score_gemma":0.00135074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003532721,"about_ca_topic_score_gemma":0.000001670188,"domain_scores_codex":[0.996159,0.0005464389,0.001058158,0.00109372,0.0004170454,0.000725692],"domain_scores_gemma":[0.997658,0.0001628497,0.000463837,0.001246431,0.0001110856,0.0003578208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004400407,0.001316103,0.0003365469,0.02091414,0.0007305755,0.00005926704,0.000177596,0.000001411036,0.00000604165,0.002437436,0.0007945317,0.9727863],"study_design_scores_gemma":[0.002202871,0.0002683516,0.002097093,0.03082004,0.0006763114,0.00004391925,0.0000173861,0.0000180138,0.000001705989,0.0004726172,0.9628668,0.0005148987],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001725213,0.9698828,0.0004044711,0.00008997191,0.02470891,0.004277873,0.0002674879,0.000125373,0.00007061927],"genre_scores_gemma":[0.000123956,0.9937875,0.000404892,0.00002940999,0.0008860276,0.001309227,0.003152329,0.0001109876,0.0001957278],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9722714,"threshold_uncertainty_score":0.9995795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1191926044931353,"score_gpt":0.4049967415376435,"score_spread":0.2858041370445082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}