{"id":"W2925092419","doi":"10.1056/nejmoa1811714","title":"Overall Survival with Fulvestrant plus Anastrozole in Metastatic Breast Cancer","year":2019,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Cancer Care Ontario","funders":"National Cancer Institute","keywords":"Anastrozole; Fulvestrant; Medicine; Oncology; Aromatase inhibitor; Metastatic breast cancer; Internal medicine; Aromatase; Breast cancer; Cancer; Tamoxifen; Estrogen receptor; Progression-free survival; Overall survival","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009748111,0.0002569508,0.0005275767,0.0002937484,0.000101,0.0001545311,0.0001880795,0.0002009942,0.0007936644],"category_scores_gemma":[0.001441635,0.00006632924,0.0006142986,0.0002544752,0.0001818199,0.0002015873,0.0002101725,0.0002800689,0.0000789917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003900675,"about_ca_system_score_gemma":0.00030085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003548351,"about_ca_topic_score_gemma":0.0009689337,"domain_scores_codex":[0.999716,0.0001329889,0.00002241753,0.00003761903,0.00005023053,0.00004084079],"domain_scores_gemma":[0.9995759,0.0001752825,0.0001297912,0.000024048,0.00002109725,0.00007388044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2631907,0.002588833,0.1920817,0.001899572,0.003687676,0.0007561689,0.0002855343,0.01074665,0.03501335,0.0002880621,0.001987866,0.4874739],"study_design_scores_gemma":[0.02904582,0.3294912,0.6085448,0.0003511689,0.004623204,0.002243575,0.0001285425,0.005067179,0.01163463,0.001310132,0.007514417,0.00004527036],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923975,0.006639438,0.0002819118,0.0001541778,0.00002690225,0.00003276326,0.0000927914,0.00001346449,0.0003611368],"genre_scores_gemma":[0.9980302,0.001400345,0.0001803772,0.00005546933,0.00004515232,0.00003221675,0.0001747709,0.000001291738,0.00008003627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009748111,"threshold_uncertainty_score":0.005155325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01613558606668913,"score_gpt":0.2899758635197193,"score_spread":0.2738402774530302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}