{"id":"W2925866291","doi":"10.2460/ajvr.80.4.416","title":"Tikhonov gamma variate adaptive regularization applied to technetium Tc 99m diethylenetriamine pentaacetic acid plasma clearance, compared with three other methods, for measuring glomerular filtration rate in cats","year":2019,"lang":"en","type":"article","venue":"American Journal of Veterinary Research","topic":"Veterinary Medicine and Surgery","field":"Veterinary","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland; Royal University Hospital; Shared Health; University of Saskatchewan","funders":"","keywords":"Plasma clearance; Renal function; Wilcoxon signed-rank test; Chemistry; Iohexol; Diethylenetriamine; CATS; Tikhonov regularization; Nuclear medicine; Urology; Medicine; Internal medicine; Mann–Whitney U test; Mathematics; Pharmacokinetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.005970429,0.0003844154,0.001089946,0.001336922,0.0001622602,0.00008149213,0.0006014885,0.0001062737,0.0001003654],"category_scores_gemma":[0.0002080164,0.0003298466,0.0001480393,0.001825676,0.0002956213,0.0003596622,0.0001793562,0.0007780282,0.00004347528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003202694,"about_ca_system_score_gemma":0.0002653454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009828303,"about_ca_topic_score_gemma":0.00001652607,"domain_scores_codex":[0.9952558,0.001363996,0.001002166,0.0006260755,0.000866089,0.0008858787],"domain_scores_gemma":[0.9969166,0.0009360596,0.0005711069,0.0006265641,0.0006477141,0.0003019454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.0747743,0.0003697131,0.002145532,0.0002070738,0.0002664051,0.0007798147,0.001401604,0.001478646,0.8762871,0.0001004782,0.0001261028,0.04206323],"study_design_scores_gemma":[0.03491502,0.4458322,0.3380745,0.00754578,0.0003972334,0.01655309,0.01823018,0.05448042,0.04402591,0.001740911,0.0335152,0.00468956],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9318594,0.0001953209,0.06506892,0.0003855537,0.0002535946,0.00160045,0.00001473465,0.00003298241,0.000589093],"genre_scores_gemma":[0.9525416,0.0000501722,0.04667497,0.00009560176,0.0002295472,0.0001748023,0.0000129599,0.000109691,0.0001106838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8322612,"threshold_uncertainty_score":0.9999154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.185658642291356,"score_gpt":0.4188121258137697,"score_spread":0.2331534835224137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}