{"id":"W2926209214","doi":"10.1016/j.str.2019.03.004","title":"A Proteomic Screen of Neuronal Cell-Surface Molecules Reveals IgLONs as Structurally Conserved Interaction Modules at the Synapse","year":2019,"lang":"en","type":"article","venue":"Structure","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":63,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Lethbridge","funders":"Division of Materials Research; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Directorate for Biological Sciences; State of New Jersey Department of Health and Senior Services; Robert Wood Johnson Foundation; National Institutes of Health; National Science Foundation","keywords":"Biology; Protein–protein interaction; Synapse; Cell biology; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001046574,0.0004359905,0.000299045,0.0003995197,0.0003367667,0.0003241224,0.000295914,0.0002796508,0.001084492],"category_scores_gemma":[0.0001525145,0.0001213245,0.0003423608,0.0003173163,0.0001729836,0.0001705217,0.000272131,0.0002835798,0.0005478543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003313289,"about_ca_system_score_gemma":0.0002040327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009652164,"about_ca_topic_score_gemma":0.001752973,"domain_scores_codex":[0.9999021,0.00001014498,0.000006336834,0.0000260201,0.00002842674,0.00002695941],"domain_scores_gemma":[0.999928,0.00001106093,0.00001777375,0.000006128671,0.00001482888,0.00002223625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009225445,0.00001354945,0.0007294247,0.00001710409,0.00001053701,0.00009380364,0.000008877751,0.00002145654,0.9982767,0.00003697821,0.00003809167,0.0006612499],"study_design_scores_gemma":[0.00002259644,0.000345958,0.07513721,0.00001294832,0.0001022399,0.001809457,0.0001365796,0.001281749,0.9172897,0.0001357195,0.00371348,0.00001233978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960952,0.0006080308,0.001666559,0.0000664612,0.000009467618,0.00001414168,0.0005680696,0.00002472322,0.0009472184],"genre_scores_gemma":[0.989628,0.0005863074,0.00418139,0.0001501368,0.000009150828,0.00002266049,0.003121133,0.0000227131,0.00227857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001084492,"threshold_uncertainty_score":0.003628016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01491241261618983,"score_gpt":0.2526398215988986,"score_spread":0.2377274089827087,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}