{"id":"W2926447864","doi":"10.1097/hs9.0000000000000185","title":"CAR‐T Cell Therapy in Diffuse Large B Cell Lymphoma: Hype and Hope","year":2019,"lang":"en","type":"review","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Sanofi Genzyme; Therakos; Celgene; Mallinckrodt Pharmaceuticals; Gilead Sciences; Sanofi; AOP Orphan; GlaxoSmithKline; Amgen","keywords":"Medicine; Chimeric antigen receptor; Cytokine release syndrome; Lymphoma; Hematopoietic stem cell transplantation; Cell therapy; Clinical trial; Oncology; Transplantation; Immunotherapy; Adverse effect; Blinatumomab; Immunology; Internal medicine; Stem cell; CD19; Antigen; Immune system; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000485214,0.0007386809,0.002785241,0.0002196701,0.00005583873,0.00006497814,0.0003341393,0.0007603567,0.004419697],"category_scores_gemma":[0.00002753116,0.0005622981,0.0005514665,0.000595851,0.00008648803,0.00006733076,0.0002115886,0.0007973171,0.0007972291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003497485,"about_ca_system_score_gemma":0.0008195252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001267159,"about_ca_topic_score_gemma":0.00005014732,"domain_scores_codex":[0.9966037,0.0002914631,0.0006800541,0.0009294572,0.0006045221,0.0008907802],"domain_scores_gemma":[0.9977859,0.0003353217,0.0002221617,0.00124776,0.00008548494,0.0003233284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001364988,0.002843291,0.0001772684,0.03250128,0.0001085956,0.0003886057,0.0002204764,2.74767e-8,0.0001436653,0.00001615421,0.003465016,0.9599991],"study_design_scores_gemma":[0.01486296,0.0003916089,0.00002557644,0.004309459,0.0002189882,0.0001189843,0.00009912381,0.000006337422,0.0001015504,0.000007388263,0.9793566,0.0005014124],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003569343,0.9563654,0.000001611371,0.00003131483,0.0002104709,0.002761345,0.0000515645,0.00006391559,0.03694502],"genre_scores_gemma":[0.000256026,0.902877,0.00007557411,0.0001595306,0.0002933303,0.0001531229,0.000132736,0.0002483013,0.09580443],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9758916,"threshold_uncertainty_score":0.9999807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05290399143292113,"score_gpt":0.3387629218292847,"score_spread":0.2858589303963636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}