{"id":"W2926447864","doi":"10.1097/hs9.0000000000000185","title":"CAR‐T Cell Therapy in Diffuse Large B Cell Lymphoma: Hype and Hope","year":2019,"lang":"en","type":"review","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Sanofi Genzyme; Therakos; Celgene; Mallinckrodt Pharmaceuticals; Gilead Sciences; Sanofi; AOP Orphan; GlaxoSmithKline; Amgen","keywords":"Medicine; Chimeric antigen receptor; Cytokine release syndrome; Lymphoma; Hematopoietic stem cell transplantation; Cell therapy; Clinical trial; Oncology; Transplantation; Immunotherapy; Adverse effect; Blinatumomab; Immunology; Internal medicine; Stem cell; CD19; Antigen; Immune system; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009646487,0.0004580445,0.0007584846,0.0008357821,0.0001458553,0.0007922639,0.0004575446,0.0009757585,0.002101239],"category_scores_gemma":[0.0007781201,0.0001284981,0.0005470763,0.0007096505,0.00030396,0.001251798,0.0003676786,0.001501224,0.0009123477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002636103,"about_ca_system_score_gemma":0.0004181939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002762469,"about_ca_topic_score_gemma":0.0006772778,"domain_scores_codex":[0.9997773,0.00006647305,0.00003652708,0.00002842265,0.00006678141,0.00002464706],"domain_scores_gemma":[0.9995961,0.0002181632,0.00006142728,0.00001249731,0.00007483287,0.00003711402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003227964,0.000118544,0.0002098866,0.008602524,0.0001151602,0.0002415285,0.00006409171,0.0004683675,0.002574817,0.002066852,0.03055033,0.9546651],"study_design_scores_gemma":[0.0002270558,0.001276704,0.001790032,0.005510658,0.0003957308,0.002118212,0.00009336259,0.0003623912,0.001240624,0.003249396,0.9837012,0.0000346627],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000544948,0.9971645,0.0001951957,0.0009317731,0.0003724364,0.000008053875,0.00002456175,0.000009031231,0.0007494072],"genre_scores_gemma":[0.003374195,0.9922864,0.0003705886,0.001788224,0.001018858,0.00002174936,0.00007215863,0.000005498396,0.001062267],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002101239,"threshold_uncertainty_score":0.007029355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05290399143292113,"score_gpt":0.3387629218292847,"score_spread":0.2858589303963636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}