{"id":"W2926499479","doi":"10.1097/sla.0000000000003284","title":"Factors Predicting Response, Perioperative Outcomes, and Survival Following Total Neoadjuvant Therapy for Borderline/Locally Advanced Pancreatic Cancer","year":2019,"lang":"en","type":"article","venue":"Annals of Surgery","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":437,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pancreas Centre (Canada)","funders":"","keywords":"Medicine; Neoadjuvant therapy; Perioperative; Gemcitabine; Surgery; Chemotherapy; FOLFIRINOX; Regimen; Pancreatic cancer; Oncology; Internal medicine; Cancer; Irinotecan; Breast cancer; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001502678,0.0002301323,0.001327864,0.0001648655,0.0001040441,0.00001511201,0.00005896972,0.0001288377,0.0001078451],"category_scores_gemma":[0.00149329,0.0001616091,0.0003194803,0.0001589419,0.00009991301,0.0001502175,0.00003490981,0.0001676424,0.000002044174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002964538,"about_ca_system_score_gemma":0.0007083043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002050948,"about_ca_topic_score_gemma":0.00001209254,"domain_scores_codex":[0.9981582,0.0001823164,0.0005115988,0.0003305686,0.0003582056,0.0004591437],"domain_scores_gemma":[0.9944705,0.004649756,0.000158253,0.0002453684,0.0003037873,0.0001723183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00438307,0.0001115281,0.9804817,0.000113156,0.000600089,0.00001114059,0.0006760408,0.000008788845,0.005773113,0.00001904951,0.0001332968,0.007689019],"study_design_scores_gemma":[0.002178687,0.0007509888,0.9920689,0.0003727332,0.00007067496,0.000002622148,0.00108837,0.0006099464,0.001881831,0.00001505123,0.0007933918,0.0001668389],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932772,0.002750069,0.00005821995,0.002106291,0.0003777597,0.001039879,0.0000626018,0.00003329635,0.000294715],"genre_scores_gemma":[0.9957137,0.001284121,0.0002440739,0.0003577048,0.00005802933,0.0001227139,0.00002973194,0.00003538153,0.002154617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01158716,"threshold_uncertainty_score":0.6590227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1736490358301666,"score_gpt":0.42568216562589,"score_spread":0.2520331297957234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}