{"id":"W2927192334","doi":"10.1038/s41598-019-42076-2","title":"A Tumor-Selective Monoclonal Antibody from Immunization with a Tumor-Associated Mucin Glycopeptide","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; College of Engineering, Michigan State University; National Cancer Institute; U.S. Department of Health and Human Services; National Institutes of Health; University of Alberta; Michigan State University","keywords":"Polyclonal antibodies; Monoclonal antibody; Epitope; Immunogen; Antiserum; Molecular biology; Antigen; Biology; MUC1; Antibody; Mucin; Glycopeptide; Immunology; Microbiology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003465943,0.0006105035,0.0003441979,0.000523572,0.0001913791,0.0002433961,0.0004130376,0.0006820211,0.001648437],"category_scores_gemma":[0.0003069323,0.0002461554,0.0004025744,0.0001913384,0.0001838697,0.0001678103,0.0003437685,0.001094379,0.000597396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003648601,"about_ca_system_score_gemma":0.0002184342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003704148,"about_ca_topic_score_gemma":0.0005254847,"domain_scores_codex":[0.9996812,0.0000439854,0.00002270047,0.00007278573,0.00006539882,0.0001139663],"domain_scores_gemma":[0.9998319,0.00004958351,0.00001795933,0.00002129319,0.00004218296,0.0000370491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000593562,0.00008849557,0.0001223468,0.00003278132,0.00000831574,0.00003517879,0.000006462855,0.00004179613,0.9972787,0.00006049798,0.00007114203,0.002194875],"study_design_scores_gemma":[0.00008529909,0.000977359,0.003060943,0.00001287463,0.00005678239,0.0003853839,0.000008388384,0.001302444,0.9904547,0.0000696343,0.003581149,0.000005027823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9730744,0.001758893,0.01824216,0.000310139,0.0001783052,0.000347326,0.0004570633,0.0002632723,0.00536843],"genre_scores_gemma":[0.9810947,0.0008770716,0.01166432,0.0002920868,0.00008142966,0.000251331,0.001447094,0.00004998779,0.004242036],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001648437,"threshold_uncertainty_score":0.005514562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00582108615457082,"score_gpt":0.2497216491253703,"score_spread":0.2439005629707995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}