{"id":"W2927760310","doi":"10.26508/lsa.201800257","title":"The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner","year":2019,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Stichting TSC Fonds; Bundesministerium für Bildung und Forschung; Rijksuniversiteit Groningen; Deutsche Forschungsgemeinschaft; European Commission; Newcastle University; Ministère de l'Économie, de la Science et de l'Innovation - Québec","keywords":"Stress granule; Granule (geology); Cell biology; MAPK/ERK pathway; p38 mitogen-activated protein kinases; PI3K/AKT/mTOR pathway; Chemistry; Biology; Signal transduction; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001579568,0.0004436291,0.0001422332,0.0003392627,0.0003528543,0.0004959262,0.0002617305,0.0001929251,0.001114925],"category_scores_gemma":[0.00009383874,0.0001655637,0.0002482038,0.0002447337,0.0004601296,0.0005428086,0.0004858146,0.0005393231,0.0004654663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005654457,"about_ca_system_score_gemma":0.000527807,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006480406,"about_ca_topic_score_gemma":0.0007585938,"domain_scores_codex":[0.9998584,0.00001219311,0.000006740157,0.00004062835,0.00004006421,0.00004190376],"domain_scores_gemma":[0.9999217,0.000005028992,0.00002761286,0.000008453997,0.00001322151,0.00002390419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001711088,0.00003054298,0.000718792,0.00007982112,0.000006901841,0.000127949,0.00004296272,0.0002960673,0.9848007,0.002819037,0.0002416468,0.01066446],"study_design_scores_gemma":[0.00006704086,0.0003009338,0.01882217,0.00002262971,0.0000331165,0.0005213587,0.0001422998,0.004227537,0.9481891,0.005008035,0.02264521,0.00002060351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8981355,0.01268953,0.06964827,0.001395878,0.0001812856,0.0001635232,0.0009545683,0.001229117,0.01560239],"genre_scores_gemma":[0.9764493,0.004034154,0.01504357,0.0001035403,0.00003697195,0.00006258327,0.0003015593,0.00003816965,0.003930229],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001114925,"threshold_uncertainty_score":0.004102588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008678143199432034,"score_gpt":0.2526846075343829,"score_spread":0.2440064643349509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}