{"id":"W2928823338","doi":"10.7759/cureus.4382","title":"Clinical Efficacy and Safety Profile of Prucalopride in Chronic Idiopathic Constipation","year":2019,"lang":"en","type":"review","venue":"Cureus","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Constipation; Prokinetic agent; Internal medicine; Chronic constipation; Tegaserod; Gastroenterology; Defecation; Adverse effect","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007238136,0.0002248714,0.001788659,0.00008322154,0.00001420164,0.000004674277,0.00009152008,0.000299283,0.00006253598],"category_scores_gemma":[0.001651859,0.000180763,0.0002233033,0.0001626445,0.000217978,0.00003525646,0.00006592313,0.0006252231,0.00005464949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001651164,"about_ca_system_score_gemma":0.001364794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002682582,"about_ca_topic_score_gemma":0.00003550755,"domain_scores_codex":[0.9979904,0.0002039132,0.001087469,0.000374258,0.0001516108,0.0001923828],"domain_scores_gemma":[0.9987051,0.0003805943,0.0003682295,0.0003808659,0.00006542278,0.00009977785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001161173,0.0002583738,0.005723457,0.0506381,0.00005233357,0.00001520537,0.00002254967,7.151898e-7,9.987355e-7,0.0001756057,0.00006155891,0.942935],"study_design_scores_gemma":[0.007090795,0.00350813,0.05846696,0.2027569,0.002525984,0.0004350026,0.00004172223,0.0001306206,0.000001005251,0.00007979945,0.7244648,0.0004982604],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001014457,0.9959029,0.00005930916,0.00002722585,0.0001512782,0.001684252,0.00002045892,0.00001935019,0.001120767],"genre_scores_gemma":[0.003596063,0.9957448,0.0003189222,0.00001591425,0.0001031664,0.00001813146,0.00009841665,0.00002191754,0.00008262943],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9424368,"threshold_uncertainty_score":0.7371303,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1005355976049763,"score_gpt":0.4127610199054557,"score_spread":0.3122254223004794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}