{"id":"W2928823338","doi":"10.7759/cureus.4382","title":"Clinical Efficacy and Safety Profile of Prucalopride in Chronic Idiopathic Constipation","year":2019,"lang":"en","type":"review","venue":"Cureus","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Constipation; Prokinetic agent; Internal medicine; Chronic constipation; Tegaserod; Gastroenterology; Defecation; Adverse effect","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006158266,0.0004519933,0.001520207,0.001417625,0.0001732523,0.0005503967,0.0007291614,0.0005883424,0.003100471],"category_scores_gemma":[0.000798016,0.0001701723,0.0007610483,0.001130493,0.000232743,0.0004621291,0.0002791417,0.0008360561,0.0006579593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002872978,"about_ca_system_score_gemma":0.000457025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006597193,"about_ca_topic_score_gemma":0.001619266,"domain_scores_codex":[0.9998226,0.00003754028,0.00003915715,0.00002576169,0.00006303738,0.00001190638],"domain_scores_gemma":[0.9997123,0.0001299403,0.00006198385,0.000005307555,0.00007162398,0.00001888507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006504058,0.0001297887,0.0004992948,0.04993673,0.0004568213,0.0003904912,0.00008619652,0.0002680438,0.002472376,0.0008051454,0.01389462,0.9304101],"study_design_scores_gemma":[0.001303971,0.003361891,0.01364727,0.02863733,0.004070481,0.01207212,0.000360054,0.0007289401,0.005043792,0.001616546,0.9290345,0.0001232838],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008437863,0.9982084,0.00004568561,0.00009368288,0.00005866764,0.000009572107,0.00003087596,0.000005039285,0.0007042891],"genre_scores_gemma":[0.007929606,0.9909864,0.000189202,0.000268358,0.00009477137,0.00001633582,0.00007156406,0.000002711949,0.000441053],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003100471,"threshold_uncertainty_score":0.01037216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1005355976049763,"score_gpt":0.4127610199054557,"score_spread":0.3122254223004794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}