{"id":"W2929339480","doi":"10.1098/rstb.2018.0288","title":"An epithelial organoid model with Langerhans cells for assessing virus-host interactions","year":2019,"lang":"en","type":"article","venue":"Philosophical Transactions of the Royal Society B Biological Sciences","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lakehead University; Thunder Bay Regional Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Northern Ontario Heritage Fund Corporation","keywords":"Biology; Organoid; Carcinogenesis; Host (biology); Innate immune system; Immune system; Virus; Cancer; Computational biology; Immunology; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006431509,0.0007058962,0.0004238395,0.0007649375,0.0004035633,0.0008384446,0.0008499694,0.001384039,0.00291149],"category_scores_gemma":[0.000361674,0.0004295038,0.0007198883,0.0005829348,0.0005398181,0.0006259826,0.0009875186,0.001660312,0.000836254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000721271,"about_ca_system_score_gemma":0.0006480572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001879654,"about_ca_topic_score_gemma":0.002170485,"domain_scores_codex":[0.9994718,0.00009922292,0.00003837793,0.0001698907,0.0001655793,0.00005512988],"domain_scores_gemma":[0.9993007,0.000224109,0.0001315193,0.0001398259,0.00007090273,0.0001329829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002120993,0.0001450842,0.001090268,0.0002310523,0.00002252799,0.0002389507,0.0001677802,0.009376911,0.9825186,0.002232814,0.0002642319,0.003499768],"study_design_scores_gemma":[0.0001043977,0.0019812,0.004923834,0.0001459068,0.000182212,0.0008337519,0.0003996185,0.08185861,0.8718498,0.00280085,0.03481409,0.0001058934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6637495,0.007545967,0.3069054,0.0007506738,0.0006691502,0.0007203773,0.00617394,0.001077064,0.01240781],"genre_scores_gemma":[0.8546574,0.003276539,0.1316361,0.000178765,0.00004272672,0.0007926227,0.001840644,0.0001374047,0.007437878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00291149,"threshold_uncertainty_score":0.009739876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07928058243008315,"score_gpt":0.3583596649154462,"score_spread":0.2790790824853631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}