{"id":"W2929346300","doi":"10.1007/978-1-4939-9158-7_3","title":"Methods to Monitor the Trafficking of β-Arrestin/G Protein-Coupled Receptor Complexes Using Enhanced Bystander BRET","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Arrestin; Endosome; G protein-coupled receptor; Cell biology; Receptor; Chemistry; Bystander effect; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001606153,0.001447388,0.0008106642,0.001311279,0.0008165521,0.001315224,0.001387781,0.001421269,0.002960707],"category_scores_gemma":[0.001068889,0.0007638173,0.0007185737,0.0007145804,0.0008629585,0.001192736,0.001031397,0.004303856,0.001884083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001254568,"about_ca_system_score_gemma":0.0004456445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000593289,"about_ca_topic_score_gemma":0.001051658,"domain_scores_codex":[0.9987115,0.0002810111,0.00008727953,0.0002726028,0.0004626226,0.0001849991],"domain_scores_gemma":[0.9990265,0.0004032976,0.0002127578,0.0001741135,0.0001162742,0.00006713007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006424738,0.00003038411,0.00008615808,0.0001063472,0.00001935967,0.00003626828,0.00005978636,0.0001168422,0.9966226,0.000855738,0.0001979968,0.001804316],"study_design_scores_gemma":[0.00003016271,0.00007453698,0.0007705772,0.00001521142,0.00001726643,0.0001901424,0.00002536445,0.00297256,0.9927415,0.0003325643,0.002809109,0.00002102466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.4134145,0.006643838,0.563661,0.001365811,0.0003590572,0.0006653419,0.00142303,0.003856875,0.008610477],"genre_scores_gemma":[0.6704862,0.01039742,0.282848,0.001077782,0.0001471069,0.002821355,0.002557247,0.001292324,0.02837261],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.002960707,"threshold_uncertainty_score":0.009904563,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02587422504465765,"score_gpt":0.3901087925170994,"score_spread":0.3642345674724418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}