{"id":"W2929560656","doi":"10.1093/cid/ciz022","title":"Safety and Pharmacokinetics of Glecaprevir/Pibrentasvir in Adults With Chronic Genotype 1–6 Hepatitis C Virus Infections and Compensated Liver Disease","year":2019,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Hepatitis C virus research","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Liver Centre","funders":"Gilead Sciences; AbbVie; Bristol-Myers Squibb","keywords":"Genotype; Pharmacokinetics; Medicine; Liver disease; Hepatitis C virus; Disease; Virology; Internal medicine; Virus; Gastroenterology; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002419442,0.0003097736,0.0007436154,0.0002647036,0.0001465851,0.000484704,0.0001959193,0.0004016227,0.001000196],"category_scores_gemma":[0.002747478,0.0001818259,0.0007255939,0.0003396693,0.0001776227,0.0004508123,0.0001968972,0.00063448,0.0001880849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003404866,"about_ca_system_score_gemma":0.0004190554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004252683,"about_ca_topic_score_gemma":0.0009709326,"domain_scores_codex":[0.9990934,0.0003975379,0.00009523091,0.0001096696,0.0002437802,0.00006025381],"domain_scores_gemma":[0.9985911,0.000359971,0.0007239248,0.00005522679,0.0001208564,0.0001489337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1365515,0.003265124,0.5910916,0.001621975,0.004653182,0.0005365491,0.0005168125,0.003560162,0.02552453,0.000177773,0.00159767,0.2309031],"study_design_scores_gemma":[0.02006285,0.09967622,0.8614583,0.0001882053,0.002539262,0.002644535,0.0001825062,0.003193696,0.005369339,0.0001946173,0.004442493,0.00004791519],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927347,0.005346068,0.0002673475,0.0001367575,0.00001168384,0.0001220414,0.0004125175,0.00001382279,0.0009550531],"genre_scores_gemma":[0.9981755,0.0006610702,0.000415877,0.0001158745,0.00002278978,0.00003572952,0.0004319771,0.000002670056,0.0001384684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002419442,"threshold_uncertainty_score":0.01279539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02074469871344217,"score_gpt":0.3423199019060881,"score_spread":0.321575203192646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}