{"id":"W2931658929","doi":"10.1080/21691401.2019.1577885","title":"ARTIFICIAL CELL evolves into nanomedicine, biotherapeutics, blood substitutes, drug delivery, enzyme/gene therapy, cancer therapy, cell/stem cell therapy, nanoparticles, liposomes, bioencapsulation, replicating synthetic cells, cell encapsulation/scaffold, biosorbent/immunosorbent haemoperfusion/plasmapheresis, regenerative medicine, encapsulated microbe, nanobiotechnology, nanotechnology","year":2019,"lang":"en","type":"review","venue":"Artificial Cells Nanomedicine and Biotechnology","topic":"Electrohydrodynamics and Fluid Dynamics","field":"Engineering","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Nanomedicine; Drug delivery; Nanobiotechnology; Liposome; Regenerative medicine; Cell therapy; Genetic enhancement; Nanotechnology; Cell; Gene delivery; Medicine; Materials science; Nanoparticle; Chemistry; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.001120406,0.003113639,0.004849536,0.003463362,0.001051399,0.0001794283,0.00238983,0.005008305,0.0001923697],"category_scores_gemma":[0.00001842022,0.002579421,0.0007268884,0.004694614,0.002478601,0.0002844703,0.0005501903,0.002729847,0.0001389347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006718425,"about_ca_system_score_gemma":0.0008318092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001307803,"about_ca_topic_score_gemma":0.0003908257,"domain_scores_codex":[0.9881613,0.0005414025,0.004334805,0.00340773,0.0009079089,0.002646837],"domain_scores_gemma":[0.9933995,0.0005364047,0.001968313,0.003142957,0.0004874907,0.0004653622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008034734,0.000700386,0.000005183415,0.001814268,0.0004198785,0.00005189521,0.0005201307,0.0003112481,0.7361099,0.0001496057,0.0005208082,0.2593164],"study_design_scores_gemma":[0.001812926,0.00130363,7.800975e-7,0.001424725,0.0009090219,0.00006234621,0.0003870644,0.005176014,0.804313,0.0001742841,0.1823375,0.002098713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2737196,0.7178254,0.0002964488,0.0008925243,0.002132546,0.003531503,0.0002700109,0.001264394,0.00006752565],"genre_scores_gemma":[0.2086664,0.7877666,0.0009873352,0.0002167484,0.00044499,0.0003495486,0.00061986,0.0005411551,0.0004074074],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.2572177,"threshold_uncertainty_score":0.9995709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01826483278443853,"score_gpt":0.2353707042348734,"score_spread":0.2171058714504349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}