{"id":"W2932093126","doi":"10.1155/2019/4050796","title":"The Role of Mitochondrial Damage-Associated Molecular Patterns in Chronic Neuroinflammation","year":2019,"lang":"en","type":"review","venue":"Mediators of Inflammation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Neuroinflammation; Neurodegeneration; Biology; Microglia; TFAM; Mitochondrion; Proinflammatory cytokine; DNAJA3; Neuroscience; Cell biology; mitochondrial fusion; Inflammation; Disease; Immunology; Mitochondrial DNA; Medicine; Mitochondrial biogenesis; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005471534,0.0004859654,0.001199307,0.0006361871,0.0001047529,0.00007702143,0.0008088462,0.0003626809,0.00003615228],"category_scores_gemma":[0.00243984,0.0003917334,0.0004433456,0.0008806121,0.0001009628,0.0003470675,0.0001498084,0.0005313428,0.00007962297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002568717,"about_ca_system_score_gemma":0.0006289007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009671065,"about_ca_topic_score_gemma":0.0000746994,"domain_scores_codex":[0.994418,0.001337374,0.002244994,0.0006001562,0.001008552,0.0003909186],"domain_scores_gemma":[0.9949351,0.001171141,0.002839172,0.0008288752,0.0001473871,0.0000783566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000322085,0.00005053593,0.00001269473,0.004467722,0.00002772495,0.00001722407,0.0002279063,0.0007057366,0.6732993,0.01067981,0.00002652248,0.3104527],"study_design_scores_gemma":[0.0008881025,0.0001854827,0.00001354418,0.002616578,0.0001927376,0.00000717694,0.00002262211,0.003596572,0.9159811,0.0004436919,0.07557139,0.0004809826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2721979,0.7062243,0.000335781,0.0002124803,0.00824916,0.0110813,0.0003605279,0.0003457123,0.0009928914],"genre_scores_gemma":[0.009544978,0.9895377,0.00002010911,0.00001099543,0.0002791804,0.0001978303,0.0001689129,0.0001105061,0.0001298555],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3099717,"threshold_uncertainty_score":0.9998534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02178985027572898,"score_gpt":0.2809342432626067,"score_spread":0.2591443929868777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}