{"id":"W2932570048","doi":"10.3390/cells8040303","title":"Combined Targeted Omic and Functional Assays Identify Phospholipases A2 that Regulate Docking/Priming in Calcium-Triggered Exocytosis","year":2019,"lang":"en","type":"article","venue":"Cells","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"National Health and Medical Research Council; Medical Research Council; Western Sydney University","keywords":"Exocytosis; Docking (animal); Phospholipase A2; Cell biology; Biology; Lipid bilayer fusion; Secretory Vesicle; Biochemistry; Chemistry; Membrane; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003015496,0.000627563,0.0004443558,0.0004358318,0.0002062368,0.0009548522,0.0002524126,0.0004712983,0.0008636003],"category_scores_gemma":[0.0002128567,0.0001939818,0.0004767524,0.0003651898,0.0003078294,0.0004679849,0.0004908066,0.0008231896,0.0003953484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004788609,"about_ca_system_score_gemma":0.00030793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003997453,"about_ca_topic_score_gemma":0.0006954647,"domain_scores_codex":[0.9997328,0.00003211951,0.00002438158,0.00006938192,0.00009012824,0.00005113795],"domain_scores_gemma":[0.9998716,0.00002612861,0.00003769776,0.00001687199,0.00002084113,0.00002687465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009816922,0.00001108191,0.0002382692,0.00002294486,0.000006837697,0.00001284589,0.000003486234,0.00005401525,0.9989175,0.00004649802,0.00001524113,0.0005733242],"study_design_scores_gemma":[0.00001022042,0.00008646308,0.007209363,0.000003390629,0.00002152115,0.0000766602,0.00002492248,0.00173759,0.9899617,0.00008871435,0.0007737185,0.000005723911],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9700952,0.002398228,0.02295971,0.0002857837,0.00006276272,0.00007512981,0.00222828,0.000293784,0.001601109],"genre_scores_gemma":[0.986522,0.001059273,0.008395521,0.0001436165,0.00001349647,0.00006443807,0.001551539,0.00004527372,0.002204809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009548522,"threshold_uncertainty_score":0.003474414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01765826689653451,"score_gpt":0.2263893104076602,"score_spread":0.2087310435111257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}