{"id":"W2932570048","doi":"10.3390/cells8040303","title":"Combined Targeted Omic and Functional Assays Identify Phospholipases A2 that Regulate Docking/Priming in Calcium-Triggered Exocytosis","year":2019,"lang":"en","type":"article","venue":"Cells","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"National Health and Medical Research Council; Medical Research Council; Western Sydney University","keywords":"Exocytosis; Docking (animal); Phospholipase A2; Cell biology; Biology; Lipid bilayer fusion; Secretory Vesicle; Biochemistry; Chemistry; Membrane; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001664323,0.0001634274,0.0001848433,0.00006930267,0.00005107914,0.00003344479,0.0000812052,0.0001892411,0.0002045955],"category_scores_gemma":[0.000006614719,0.0001689271,0.00008659606,0.00008080502,0.00004632557,0.000009158935,0.00004464856,0.0001029011,0.00003300836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002244075,"about_ca_system_score_gemma":0.00003757864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007888617,"about_ca_topic_score_gemma":0.00003270152,"domain_scores_codex":[0.9990096,0.00003196537,0.000200132,0.0003869411,0.0001354027,0.0002359679],"domain_scores_gemma":[0.9995686,0.00001459969,0.00007353345,0.0002397173,0.00003340542,0.00007009415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001814078,0.00003840822,0.03934087,0.000034413,0.00002491984,0.000006659155,0.00004985062,0.0001372759,0.9598172,0.0000201938,0.0001718014,0.0001769952],"study_design_scores_gemma":[0.001368441,0.00007299661,0.1040533,0.00002834563,0.00002269204,0.000003607561,0.00005557318,0.0002988078,0.8891605,0.00005779481,0.004659773,0.0002181596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974117,0.000809581,0.0007448298,0.00004350278,0.0004066648,0.0002225226,0.00001482267,0.00001454754,0.0003317741],"genre_scores_gemma":[0.9969285,0.000220191,0.00005743766,0.0000995864,0.00007041862,0.000008689207,0.001560839,0.00002318791,0.001031207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07065668,"threshold_uncertainty_score":0.6888645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01765826689653451,"score_gpt":0.2263893104076602,"score_spread":0.2087310435111257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}