{"id":"W2932781706","doi":"10.1093/biolre/ioz053","title":"Formation of organotypic testicular organoids in microwell culture†","year":2019,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Alberta; University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health; Society for the Study of Reproduction","keywords":"Organoid; Biology; Cell biology; Sertoli cell; Retinoic acid; Germ cell; Cell culture; Spermatogenesis; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002084107,0.00006559685,0.000196887,0.0001272456,0.000008296942,7.632356e-7,0.00002660985,0.000114717,0.00009178905],"category_scores_gemma":[0.0003786435,0.00005296559,0.0000373487,0.0002528555,0.00005434619,0.00005850966,0.00001136308,0.00007545871,0.00004490055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003355369,"about_ca_system_score_gemma":0.00002891916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000359428,"about_ca_topic_score_gemma":0.00000197674,"domain_scores_codex":[0.9993694,0.00003022728,0.000247284,0.0002146751,0.0000567264,0.00008165528],"domain_scores_gemma":[0.9993978,0.00001232405,0.000133119,0.0002817351,0.0001597442,0.00001535183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008000212,0.00008806636,0.1740043,0.000114633,0.000009644661,5.513775e-7,0.0001328315,0.000008270335,0.8221192,0.0001526363,0.00009580264,0.003194046],"study_design_scores_gemma":[0.0007886107,0.000543329,0.1377252,0.00005701717,0.00003371218,0.0001136864,0.000103646,0.0000559638,0.8575292,0.000251365,0.002744128,0.00005403623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969141,0.001234919,0.000530159,0.0001820787,0.0003752261,0.0002893937,0.000001104652,0.0000217439,0.0004512547],"genre_scores_gemma":[0.9981135,0.00008889205,0.001348393,0.00001380029,0.00008536378,0.000002686634,0.00006809719,0.000006137651,0.0002731474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03627901,"threshold_uncertainty_score":0.2159874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009430680099444753,"score_gpt":0.2380181530099668,"score_spread":0.2285874729105221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}