{"id":"W2932781706","doi":"10.1093/biolre/ioz053","title":"Formation of organotypic testicular organoids in microwell culture†","year":2019,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Alberta; University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health; Society for the Study of Reproduction","keywords":"Organoid; Biology; Cell biology; Sertoli cell; Retinoic acid; Germ cell; Cell culture; Spermatogenesis; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001066567,0.001287215,0.001086937,0.0006071907,0.0006716161,0.001008641,0.001488192,0.0009657775,0.002767714],"category_scores_gemma":[0.0003017566,0.0006609675,0.001500188,0.0004954739,0.0004507326,0.0005357075,0.0009929829,0.002122288,0.003690028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000491315,"about_ca_system_score_gemma":0.0005721775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001497433,"about_ca_topic_score_gemma":0.00413056,"domain_scores_codex":[0.9988407,0.0001644336,0.0001806457,0.0002897311,0.0003093823,0.0002151018],"domain_scores_gemma":[0.999135,0.0001788336,0.0001530763,0.0002258893,0.0001506945,0.0001566272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005114347,0.00005571349,0.0002272971,0.0002033345,0.00002185464,0.0001695702,0.00008324022,0.0006843191,0.9939283,0.000625145,0.000554427,0.003395717],"study_design_scores_gemma":[0.0000167801,0.0001938962,0.001449264,0.00003441832,0.00004459995,0.0002953357,0.00004345534,0.004543208,0.9742233,0.00016845,0.01894785,0.00003954586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.231007,0.008688393,0.7124727,0.0006924431,0.00176111,0.003447047,0.01498984,0.00590758,0.02103384],"genre_scores_gemma":[0.4397398,0.007571276,0.5125495,0.0005422102,0.0001759824,0.004361939,0.01418695,0.0008531677,0.02001918],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002767714,"threshold_uncertainty_score":0.009258926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009430680099444753,"score_gpt":0.2380181530099668,"score_spread":0.2285874729105221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}