{"id":"W2932902987","doi":"10.1038/s41564-019-0411-z","title":"Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus","year":2019,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"Viral Infections and Vectors","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Institute of Biophysics, Chinese Academy of Sciences; Youth Innovation Promotion Association; National Science and Technology Major Project; Youth Innovation Promotion Association of the Chinese Academy of Sciences; China Scholarship Council; University of Texas Health Science Center at Houston; Chinese Academy of Sciences; Tsinghua University; National Natural Science Foundation of China; China Association for Science and Technology","keywords":"Monoclonal antibody; Virology; Epitope; Antibody; Biology; Neutralization; Antigen; Rift Valley fever; Virus; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003729303,0.0003834051,0.0002223214,0.0002373481,0.0002017013,0.0003546409,0.0006340104,0.0005114458,0.001484652],"category_scores_gemma":[0.0003024611,0.0001732541,0.0004005664,0.00006612034,0.0002769336,0.0003532845,0.0002361552,0.0005340704,0.0003370998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006237249,"about_ca_system_score_gemma":0.0001612171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001048571,"about_ca_topic_score_gemma":0.0003853317,"domain_scores_codex":[0.9997894,0.00004667489,0.000006262439,0.00003410141,0.00003085016,0.00009262389],"domain_scores_gemma":[0.9998636,0.00005823914,0.00001676425,0.00001690674,0.00002767543,0.00001678942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002802862,0.00005902423,0.0004194779,0.00005880264,0.00002096673,0.0001158954,0.00004053922,0.0003243109,0.9932041,0.001634228,0.000135808,0.003706679],"study_design_scores_gemma":[0.0001883311,0.001361552,0.003945763,0.00002005469,0.00005825815,0.00117887,0.00004966416,0.008750289,0.9777129,0.0008379557,0.005878693,0.0000175679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984979,0.002497967,0.006971393,0.0001474934,0.00007383132,0.00006715364,0.00007104598,0.00007787455,0.005114229],"genre_scores_gemma":[0.9976844,0.0003049459,0.0007369529,0.00007636375,0.00001220938,0.00001319162,0.00007919595,0.000004326116,0.001088428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001484652,"threshold_uncertainty_score":0.004966676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00862101983524043,"score_gpt":0.2778673000936944,"score_spread":0.269246280258454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}