{"id":"W2932943714","doi":"10.1161/circresaha.118.314284","title":"Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction","year":2019,"lang":"en","type":"article","venue":"Circulation Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Queen's University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Hypoxic pulmonary vasoconstriction; Vasoconstriction; Hypoxia (environmental); Mitochondrion; Protein subunit; Oxygen; Cardiology; Pulmonary hypertension; Chemistry; Medicine; Internal medicine; Pharmacology; Biology; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002687892,0.0001029722,0.0001666428,0.0001698971,0.0001431558,0.00002647015,0.00008667876,0.0002257942,0.0001608369],"category_scores_gemma":[0.00009542627,0.0001097678,0.00008727781,0.0002025857,0.0001416096,0.000007966616,0.00007612917,0.0001222624,0.00001977579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001539634,"about_ca_system_score_gemma":0.00009455247,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004356598,"about_ca_topic_score_gemma":0.00001182843,"domain_scores_codex":[0.9987734,0.0001258865,0.0002364094,0.0003893215,0.0002301815,0.0002448013],"domain_scores_gemma":[0.9990365,0.00007770859,0.00008296475,0.0002839241,0.0004455673,0.00007332372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003510141,0.00003059358,0.003688486,0.00003719118,0.00006258209,0.00000138392,0.00005469867,0.00006235008,0.9911357,0.0001943748,0.001738394,0.002643202],"study_design_scores_gemma":[0.01248334,0.003359221,0.07841954,0.000134,0.0003124614,0.000672165,0.001243506,0.1375705,0.6565924,0.00443015,0.1033279,0.001454796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983751,0.0001011403,0.01353977,0.000159286,0.0005781399,0.0008831213,0.00005980859,0.000009694028,0.0009180738],"genre_scores_gemma":[0.9966164,0.00006892824,0.001439149,0.00007283956,0.0004981609,0.00001750126,0.0004452066,0.00001979649,0.000822081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3345433,"threshold_uncertainty_score":0.44762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07435302120053315,"score_gpt":0.3630942471856016,"score_spread":0.2887412259850684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}