{"id":"W2932943714","doi":"10.1161/circresaha.118.314284","title":"Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction","year":2019,"lang":"en","type":"article","venue":"Circulation Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Queen's University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Hypoxic pulmonary vasoconstriction; Vasoconstriction; Hypoxia (environmental); Mitochondrion; Protein subunit; Oxygen; Cardiology; Pulmonary hypertension; Chemistry; Medicine; Internal medicine; Pharmacology; Biology; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001943827,0.0004263009,0.0002404816,0.0001263216,0.0002399153,0.0003228773,0.0002112308,0.0004123907,0.001619523],"category_scores_gemma":[0.0003550933,0.0001577753,0.0001513066,0.0001032473,0.0004109404,0.0002027949,0.0001916428,0.0003792372,0.0002709293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00046655,"about_ca_system_score_gemma":0.0003200077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009566525,"about_ca_topic_score_gemma":0.001239249,"domain_scores_codex":[0.9998481,0.00001994321,0.00001398747,0.00003952083,0.0000438059,0.0000345765],"domain_scores_gemma":[0.9997481,0.00003930932,0.00009365036,0.00001785843,0.00002871861,0.00007243658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004303123,0.00003997441,0.001626965,0.0001080316,0.000007320016,0.0001526553,0.00001622628,0.00006262679,0.9953785,0.0001515948,0.0001803534,0.001845512],"study_design_scores_gemma":[0.0001130441,0.001267493,0.08282784,0.00005601477,0.00007676717,0.002274782,0.0001513937,0.002515712,0.8974471,0.0003116911,0.01294315,0.00001482662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822212,0.007473783,0.006693798,0.0008371345,0.0001269578,0.00008175049,0.0006733786,0.0001495162,0.001742565],"genre_scores_gemma":[0.9951074,0.001298874,0.001658,0.00008293304,0.00003290459,0.00003700939,0.0003964801,0.0000066752,0.001379733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001619523,"threshold_uncertainty_score":0.005417824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07435302120053315,"score_gpt":0.3630942471856016,"score_spread":0.2887412259850684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}