{"id":"W2934758797","doi":"10.1074/jbc.ra119.007426","title":"A chloride ring is an ancient evolutionary innovation mediating the assembly of the collagen IV scaffold of basement membranes","year":2019,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Vanderbilt University","keywords":"Random hexamer; Trimer; Chemistry; Chloride; Basement membrane; Extracellular matrix; Biophysics; Cell biology; Biochemistry; Biology; Dimer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000349047,0.0002987054,0.0002790279,0.0003150825,0.0003650817,0.0005765381,0.0005485532,0.0007124463,0.0007410411],"category_scores_gemma":[0.0002320667,0.0002224208,0.0002918048,0.0002135025,0.0006960608,0.0006895353,0.000431981,0.0006189278,0.0005283396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005559007,"about_ca_system_score_gemma":0.0004510033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006064819,"about_ca_topic_score_gemma":0.0006486409,"domain_scores_codex":[0.9997445,0.00003314006,0.00001548878,0.00009761401,0.00007577049,0.00003350391],"domain_scores_gemma":[0.999838,0.00001847917,0.00006493212,0.00002190725,0.00002597633,0.00003064235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004719363,0.000007459123,0.0005632284,0.00007578846,0.000004898418,0.0001508528,0.0000416362,0.000106918,0.9914628,0.001503994,0.00007189152,0.005963414],"study_design_scores_gemma":[0.00001963347,0.000359529,0.007637297,0.00003450648,0.00003477274,0.001288274,0.00008157847,0.001711997,0.9579917,0.000900345,0.02990133,0.00003914996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9026776,0.01751457,0.06471296,0.001175485,0.0003494181,0.0001076323,0.0006564842,0.000703579,0.01210232],"genre_scores_gemma":[0.9622644,0.005322758,0.02523587,0.0002267137,0.00007986478,0.00003674492,0.0003174592,0.00006309503,0.006453154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007410411,"threshold_uncertainty_score":0.004033387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04200669447686062,"score_gpt":0.3030961905186471,"score_spread":0.2610894960417865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}