{"id":"W2934758797","doi":"10.1074/jbc.ra119.007426","title":"A chloride ring is an ancient evolutionary innovation mediating the assembly of the collagen IV scaffold of basement membranes","year":2019,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Vanderbilt University","keywords":"Random hexamer; Trimer; Chemistry; Chloride; Basement membrane; Extracellular matrix; Biophysics; Cell biology; Biochemistry; Biology; Dimer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00107376,0.00008861745,0.0002616688,0.00004172338,0.00004484232,0.000006018368,0.0002893636,0.0001045992,0.0003214398],"category_scores_gemma":[0.0009459227,0.00004117766,0.0001327422,0.0004654204,0.000108991,0.00003563354,0.0001327398,0.0002139429,0.000001637615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009609012,"about_ca_system_score_gemma":0.0002163435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005393158,"about_ca_topic_score_gemma":1.353689e-7,"domain_scores_codex":[0.9983731,0.0000604174,0.0006152561,0.0001207801,0.000678409,0.0001520624],"domain_scores_gemma":[0.9982188,0.000197033,0.0005985149,0.0002518893,0.0006713192,0.00006238161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002399057,0.0001411068,0.03306467,0.0001628605,0.00003741192,0.000004960825,0.00007689148,0.0000428732,0.965822,0.000007714468,0.0001818426,0.0002178044],"study_design_scores_gemma":[0.000560987,0.0002283876,0.0658304,0.000134393,0.00002022916,0.00005703392,0.000588027,0.0005677398,0.9315684,0.00002629022,0.0003759709,0.00004207477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976991,0.0003113302,0.00001014664,0.000917519,0.00007005635,0.0001672536,0.000006294718,0.000003033011,0.0008152386],"genre_scores_gemma":[0.9991784,0.00006911437,0.0001917246,0.0002083587,0.0001766005,0.000002299079,0.000004655423,0.000005143186,0.0001636769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03425349,"threshold_uncertainty_score":0.351954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04200669447686062,"score_gpt":0.3030961905186471,"score_spread":0.2610894960417865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}