{"id":"W2935450307","doi":"10.21037/hbsn.2019.03.21","title":"Signal transducer and activator of transcriptions (STATs)—at the crossroads of obesity-linked non-alcoholic steatohepatitis and hepatocellular carcinoma","year":2019,"lang":"en","type":"letter","venue":"HepatoBiliary Surgery and Nutrition","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Research Manitoba; Health Sciences Centre Foundation","keywords":"Medicine; Steatohepatitis; Hepatocellular carcinoma; Activator (genetics); Obesity; Internal medicine; Fatty liver; Cancer research; Disease; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002426983,0.0004236755,0.001135933,0.0002487726,0.0001773051,0.00002708092,0.00005418065,0.0004982145,0.000159919],"category_scores_gemma":[0.00001218392,0.0003256284,0.0004003492,0.0001647916,0.0004782997,0.0001714892,0.00003368403,0.000463323,0.000002575754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006862172,"about_ca_system_score_gemma":0.0001454491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007279519,"about_ca_topic_score_gemma":0.00002444228,"domain_scores_codex":[0.9978837,0.0002189867,0.0006139278,0.000582587,0.0003829731,0.000317793],"domain_scores_gemma":[0.9982291,0.0008389385,0.0002504863,0.0003998361,0.0001471055,0.0001344707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005445064,0.0008542063,0.9334933,0.00657559,0.0004589761,0.0002905274,0.0005169712,6.540338e-8,0.004443815,0.000005052737,0.05199762,0.0008194033],"study_design_scores_gemma":[0.00488365,0.0009368759,0.9171064,0.00321546,0.003245312,0.0002952791,0.0001730854,0.0002565206,0.03363817,0.0001320401,0.03542523,0.0006919772],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9652364,0.01091285,0.000005589078,0.02042211,0.0001360286,0.001750548,0.001485016,0.00001811974,0.00003328585],"genre_scores_gemma":[0.9756578,0.01373712,0.00001554063,0.008442754,0.0002690218,0.0002513448,0.001430016,0.00005071396,0.0001457553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02919436,"threshold_uncertainty_score":0.9999196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02137552070634884,"score_gpt":0.2288127626357079,"score_spread":0.207437241929359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}