{"id":"W2935972028","doi":"10.1101/612051","title":"Centromere clustering stabilizes meiotic homolog pairing","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fonds de Recherche du Québec - Santé; Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale; National Science Foundation; National Institutes of Health; Agence Nationale de la Recherche","keywords":"Synapsis; Meiosis; Homologous chromosome; Centromere; Genetics; Biology; Synaptonemal complex; Pairing; Bivalent (engine); Chromosome segregation; Chromosomal crossover; Chromosome; Gene; Chemistry; Physics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001105862,0.0002121627,0.0001823932,0.0002346087,0.0001951522,0.0003466942,0.0003074976,0.000258235,0.001310865],"category_scores_gemma":[0.0001488596,0.0001790645,0.0001179648,0.00008542255,0.0002150261,0.0001158749,0.0003406638,0.0003378855,0.0005343742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004331168,"about_ca_system_score_gemma":0.0002349548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009169229,"about_ca_topic_score_gemma":0.001305029,"domain_scores_codex":[0.9998531,0.0000116333,0.000008518435,0.00003529362,0.00005615367,0.00003531908],"domain_scores_gemma":[0.9998437,0.00001752785,0.00004328916,0.00002882525,0.00002021239,0.00004640844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002673903,0.000005430716,0.0003007917,0.00001103314,0.000003465718,0.00002528931,0.000004156138,0.00005465316,0.9988851,0.0001671234,0.00001889539,0.0004972124],"study_design_scores_gemma":[0.000005056546,0.00004725824,0.00589132,0.000003716443,0.000005287614,0.0001102451,0.00001468227,0.001267444,0.9912733,0.00007814106,0.00130082,0.000002647788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963914,0.0002944659,0.001569682,0.00003230101,0.000008187446,0.000004810393,0.00007893349,0.00008402738,0.00153613],"genre_scores_gemma":[0.9978001,0.00005567401,0.0004851361,0.00001115264,0.000001446474,0.000002786506,0.0001089905,0.00001453538,0.001520244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001310865,"threshold_uncertainty_score":0.004385233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01011848910828293,"score_gpt":0.2115920927247404,"score_spread":0.2014736036164575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}