{"id":"W2936026527","doi":"10.1002/adhm.201900002","title":"Effects of Programmed Local Delivery from a Micro/Nano‐Hierarchical Surface on Titanium Implant on Infection Clearance and Osteogenic Induction in an Infected Bone Defect","year":2019,"lang":"en","type":"article","venue":"Advanced Healthcare Materials","topic":"Bone Tissue Engineering Materials","field":"Engineering","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Chongqing Postdoctoral Science Special Foundation; China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Implant; Titanium; Nano-; Materials science; Delivery system; Nanotechnology; Biomedical engineering; Medicine; Composite material; Metallurgy; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000106604,0.0002252808,0.0001437153,0.0001345705,0.00006290263,0.0001667636,0.0001473132,0.0002022607,0.0005908478],"category_scores_gemma":[0.00008672207,0.0001379446,0.0001885203,0.0000525537,0.0001825884,0.0001070643,0.0001490217,0.0002037741,0.00009449189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001185243,"about_ca_system_score_gemma":0.0001133499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003476506,"about_ca_topic_score_gemma":0.0005670583,"domain_scores_codex":[0.9999186,0.00001072428,0.000006213619,0.00001656279,0.00002578005,0.00002219168],"domain_scores_gemma":[0.9999341,0.00001409331,0.00002152681,0.000006800418,0.000009163163,0.00001429991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007283896,0.00003342153,0.00004347592,0.00002224545,0.000002166995,0.00001824111,0.000007954382,0.000103038,0.9988299,0.00001951979,0.000008741737,0.0008384409],"study_design_scores_gemma":[0.00001546474,0.0006952517,0.000666248,0.000001872927,0.000008633593,0.00003267364,0.00001120264,0.001039327,0.9972624,0.000008309729,0.0002548289,0.000003839136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979505,0.0002012302,0.001491791,0.00001333172,0.00001337812,0.0000158049,0.00002048609,0.00003355791,0.0002598959],"genre_scores_gemma":[0.99703,0.0001229407,0.002133581,0.0000207179,0.00000494836,0.00001971343,0.00002398588,0.000009238891,0.0006347623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005908478,"threshold_uncertainty_score":0.001976609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006119155029645646,"score_gpt":0.2298596785218904,"score_spread":0.2237405234922448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}