{"id":"W2936913202","doi":"10.1182/bloodadvances.2018030577","title":"Targeting CD47 in Sézary syndrome with SIRPαFc","year":2019,"lang":"en","type":"article","venue":"Blood Advances","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trillium Therapeutics (Canada)","funders":"National Cancer Institute","keywords":"CD47; Phagocytosis; Lymphoma; Decoy; Medicine; Cutaneous T-cell lymphoma; Cancer research; Immunology; Receptor; Internal medicine; Mycosis fungoides","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002545352,0.0002381833,0.0004286462,0.0001514619,0.00008690552,0.0003001658,0.0001718228,0.0003405386,0.001207373],"category_scores_gemma":[0.0001271357,0.00007717326,0.0002441639,0.0001708387,0.0002460024,0.0001934441,0.0001826837,0.0005507363,0.0003911665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002422388,"about_ca_system_score_gemma":0.0002280518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003154522,"about_ca_topic_score_gemma":0.0006782034,"domain_scores_codex":[0.999929,0.00002389901,0.000005192415,0.000006962899,0.00001259693,0.00002226299],"domain_scores_gemma":[0.9999632,0.000008093743,0.00001053666,0.000004468293,0.000002493603,0.00001127002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02668572,0.00211475,0.01178482,0.0009914967,0.000307029,0.004513883,0.0002544097,0.002419997,0.626995,0.003069237,0.005591069,0.3152725],"study_design_scores_gemma":[0.03237915,0.1071088,0.07037658,0.0003927237,0.001337696,0.0342305,0.0006072425,0.01793138,0.5598726,0.002838822,0.1728495,0.00007493658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9786699,0.01546765,0.001313143,0.0006671211,0.00007806088,0.0001463926,0.0001010669,0.00008646471,0.003470271],"genre_scores_gemma":[0.9937485,0.004094777,0.0006246556,0.0001956809,0.00003223688,0.00007875529,0.0001678548,0.000005732873,0.00105172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001207373,"threshold_uncertainty_score":0.004039109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009672638446286328,"score_gpt":0.2801466938646356,"score_spread":0.2704740554183492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}