{"id":"W2936932699","doi":"10.1038/s41419-019-1567-4","title":"Influenza a virus-triggered autophagy decreases the pluripotency of human-induced pluripotent stem cells","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital; Children's Hospital Research Institute of Manitoba; University of Manitoba; Research Manitoba","funders":"Canadian Institutes of Health Research; Government of Canada; University of Manitoba; Research Manitoba","keywords":"Induced pluripotent stem cell; Biology; Autophagy; Embryonic stem cell; Cell biology; Stem cell; Cellular differentiation; Virology; Immunology; Genetics; Gene; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000108028,0.0001638841,0.0001501649,0.00003606116,0.00009264597,0.00002722153,0.0001524119,0.0000849076,0.00003626114],"category_scores_gemma":[0.00002220487,0.0001225963,0.0001148664,0.00005553328,0.00004282183,0.000004675867,0.00009661416,0.00005549521,0.00001368791],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006687584,"about_ca_system_score_gemma":0.000124918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005923048,"about_ca_topic_score_gemma":0.000005144522,"domain_scores_codex":[0.9990147,0.00007224374,0.000244522,0.0003191671,0.000150403,0.0001990178],"domain_scores_gemma":[0.999023,0.00002208704,0.0001249415,0.0004555901,0.00007675248,0.0002975937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001213725,0.0001156312,0.009060653,0.00007668366,0.00001897098,0.000003036937,0.00003658147,0.00006954145,0.9891071,0.000116563,0.00004742115,0.001226444],"study_design_scores_gemma":[0.0008760683,0.0002664278,0.01966355,0.00001673264,0.00007163418,3.19151e-7,0.00005767518,0.0001337154,0.9751059,0.0004500226,0.003173336,0.0001846013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878228,0.01084071,0.00006534622,0.00001511755,0.00009639462,0.0003458924,0.0000391281,0.000008686107,0.0007658738],"genre_scores_gemma":[0.9985241,0.0005073291,0.0000397905,0.0001888386,0.00007284506,0.00001664629,0.00003511746,0.00001843959,0.0005968444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01400119,"threshold_uncertainty_score":0.4999332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01647549194280888,"score_gpt":0.2531469539540462,"score_spread":0.2366714620112374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}