{"id":"W2936932699","doi":"10.1038/s41419-019-1567-4","title":"Influenza a virus-triggered autophagy decreases the pluripotency of human-induced pluripotent stem cells","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital; Children's Hospital Research Institute of Manitoba; University of Manitoba; Research Manitoba","funders":"Canadian Institutes of Health Research; Government of Canada; University of Manitoba; Research Manitoba","keywords":"Induced pluripotent stem cell; Biology; Autophagy; Embryonic stem cell; Cell biology; Stem cell; Cellular differentiation; Virology; Immunology; Genetics; Gene; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001036312,0.0001443727,0.0001056004,0.0001378046,0.00008914382,0.0001719456,0.00006262277,0.0001269624,0.0007462156],"category_scores_gemma":[0.00008827707,0.00006380005,0.0001950855,0.0001084809,0.0000928184,0.0001144074,0.0001182251,0.0002026429,0.0001410794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001144116,"about_ca_system_score_gemma":0.0001375982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003834809,"about_ca_topic_score_gemma":0.0006745099,"domain_scores_codex":[0.9999245,0.00001189692,0.0000130983,0.0000165613,0.00002095326,0.00001287212],"domain_scores_gemma":[0.9999617,0.000007378638,0.00001229768,0.000005318238,0.000006170277,0.000007064024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004246701,0.000007780326,0.0004345137,0.00002430523,0.000004697897,0.00002745854,0.0000126449,0.00003054863,0.9977975,0.00006155481,0.00002348803,0.001533144],"study_design_scores_gemma":[0.000006024621,0.0001973365,0.01705146,0.000006417171,0.00001640569,0.0001687747,0.00003862701,0.0007712056,0.9796855,0.00006443064,0.001990407,0.000003373839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936638,0.00212499,0.002276469,0.00006829917,0.00002623497,0.00001721434,0.0005383603,0.00004853345,0.001236231],"genre_scores_gemma":[0.9957917,0.0009648086,0.001206341,0.00005319891,0.000004558385,0.00001955957,0.0006019818,0.000007937721,0.001350025],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007462156,"threshold_uncertainty_score":0.002496362,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01647549194280888,"score_gpt":0.2531469539540462,"score_spread":0.2366714620112374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}