{"id":"W2937762300","doi":"10.1016/j.eururo.2019.04.005","title":"Separating the Dreadful from the Merely Bad: Towards Prognostic and Predictive Biomarkers in Metastatic Castration-resistant Prostate Cancer","year":2019,"lang":"en","type":"letter","venue":"European Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Medicine; Prostate cancer; Oncology; Castration; Internal medicine; Prostate; Cancer; Gynecology; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005124733,0.0006782183,0.002240997,0.0008619315,0.002881585,0.003810667,0.001133976,0.02888247,0.002441249],"category_scores_gemma":[0.03058577,0.0006275378,0.0009214929,0.0008524152,0.0025683,0.00401722,0.001592333,0.03027879,0.003329729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004551994,"about_ca_system_score_gemma":0.004832787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005235615,"about_ca_topic_score_gemma":0.009185067,"domain_scores_codex":[0.9956096,0.002009478,0.0006321496,0.0003335251,0.0009518822,0.0004634323],"domain_scores_gemma":[0.9877352,0.008117665,0.0005682218,0.0002865447,0.001827781,0.001464479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002906474,0.00009979357,0.004679401,0.0001536471,0.00004578238,0.002091175,0.0002076995,0.0001423325,0.0003647632,0.004445647,0.9380285,0.04945061],"study_design_scores_gemma":[0.0005497097,0.0003642675,0.00875794,0.001114963,0.0001571596,0.005375477,0.001203274,0.002558486,0.0005972479,0.0392439,0.9398687,0.0002088678],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0004965964,0.002116388,0.00009855098,0.9861559,0.009913623,0.000006979748,0.00004338889,0.00001079129,0.001157778],"genre_scores_gemma":[0.01233452,0.003658541,0.000478182,0.9097289,0.06929444,0.00004723965,0.00007246359,0.00002340643,0.004362203],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02888247,"threshold_uncertainty_score":0.03302717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03304992946873519,"score_gpt":0.3061657694597973,"score_spread":0.2731158399910621,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}