{"id":"W2937762300","doi":"10.1016/j.eururo.2019.04.005","title":"Separating the Dreadful from the Merely Bad: Towards Prognostic and Predictive Biomarkers in Metastatic Castration-resistant Prostate Cancer","year":2019,"lang":"en","type":"letter","venue":"European Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Medicine; Prostate cancer; Oncology; Castration; Internal medicine; Prostate; Cancer; Gynecology; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006823746,0.0003924049,0.000501262,0.0001176331,0.000164657,0.0000856546,0.0002824412,0.0001384192,0.0001221151],"category_scores_gemma":[0.0002729852,0.0001985142,0.00009130277,0.0002345192,0.0005338796,0.00006060801,0.0001669269,0.001661429,0.00006630008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001250685,"about_ca_system_score_gemma":0.0005303706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001109991,"about_ca_topic_score_gemma":0.0002047519,"domain_scores_codex":[0.9963328,0.001536791,0.0004491893,0.000680225,0.0004118161,0.0005891341],"domain_scores_gemma":[0.997869,0.001227409,0.0002352758,0.0004992973,0.0001184647,0.00005062135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00490949,0.0001487442,0.06186861,0.0004738312,0.005502652,0.010324,0.01206989,0.00009847544,0.001212438,0.000009682735,0.8897145,0.01366765],"study_design_scores_gemma":[0.005337727,0.002091906,0.4431626,0.0004574378,0.002037643,0.0001568855,0.0006209153,0.0009458517,0.00007474965,0.0001141912,0.5444994,0.0005006407],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.175815,0.01932717,0.0000108938,0.7929369,0.0005368838,0.004368325,0.001263565,0.00005559498,0.005685663],"genre_scores_gemma":[0.6941463,0.001893275,0.0001019871,0.2938028,0.001837711,0.0006523326,0.00244368,0.0002477065,0.004874191],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.5183313,"threshold_uncertainty_score":0.8095173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03304992946873519,"score_gpt":0.3061657694597973,"score_spread":0.2731158399910621,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}