{"id":"W2938013723","doi":"10.1016/s2468-1253(19)30119-0","title":"A global scientific strategy to cure hepatitis B","year":2019,"lang":"en","type":"article","venue":"˜The œLancet. Gastroenterology & hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":495,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Liver Centre; Toronto General Hospital; University of Toronto","funders":"Janssen Pharmaceuticals; National Institute of Allergy and Infectious Diseases; Abbott Diagnostics; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Gilead Sciences; Sanofi; GlaxoSmithKline; Institute of Infection and Immunity; Australian Academy of Science; Bristol-Myers Squibb","keywords":"Medicine; Hepatitis B virus; Hepatitis B; HBsAg; Malaria; Public health; Virology; Immunology; Human immunodeficiency virus (HIV); cccDNA; Virus; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005477185,0.0004337176,0.001421216,0.0001901857,0.0002982997,0.00006065049,0.0006344682,0.0002532654,0.0005798934],"category_scores_gemma":[0.00007337045,0.0003393348,0.0002177553,0.000496824,0.000760078,0.00009138767,0.0004488256,0.0005196625,0.002351949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002778923,"about_ca_system_score_gemma":0.0002069104,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001669637,"about_ca_topic_score_gemma":0.05655491,"domain_scores_codex":[0.9959236,0.0003885572,0.0006232436,0.001013579,0.0003892423,0.00166179],"domain_scores_gemma":[0.9977929,0.00009114319,0.0001885288,0.001335764,0.0002775854,0.0003140598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008634479,0.0001305608,0.9242614,0.00005179423,0.0002362049,0.0002008142,0.0001654981,0.00002689616,0.000531566,0.0006873909,0.07176615,0.001078277],"study_design_scores_gemma":[0.003020149,0.003410891,0.9153686,0.00005575781,0.0001600403,0.00143414,0.00005860308,0.0006478936,0.00003844475,0.0005231688,0.07507233,0.0002100545],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9767542,0.0002822358,0.0006845564,0.01543635,0.002234843,0.001091191,0.0001608154,0.0002026502,0.003153196],"genre_scores_gemma":[0.9813908,0.0001053351,0.0006247537,0.01617845,0.0005101527,0.0001639665,0.00005570819,0.00003874008,0.000932039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05488528,"threshold_uncertainty_score":0.9999059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02411914189982917,"score_gpt":0.2933648535579098,"score_spread":0.2692457116580806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}