{"id":"W2938084848","doi":"10.1016/j.joca.2019.02.667","title":"microRNA 27B-3P: role in extracellular matrix regulation in osteoarthritis synovial fibroblasts","year":2019,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Osteoarthritis; Extracellular matrix; Fibrosis; microRNA; In situ hybridization; Synovial fluid; Pathology; Medicine; Synovial membrane; Synovial joint; Cancer research; Chemistry; Internal medicine; Arthritis; Messenger RNA; Cell biology; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004338504,0.000477628,0.000497496,0.0006027139,0.0005442107,0.0009110915,0.0002542795,0.0005407477,0.002041267],"category_scores_gemma":[0.0005161274,0.0003405191,0.0004565045,0.0002846558,0.000452447,0.0002285165,0.0005143049,0.0006644242,0.0008110335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005282563,"about_ca_system_score_gemma":0.000788172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001437049,"about_ca_topic_score_gemma":0.00140907,"domain_scores_codex":[0.9994729,0.0001159351,0.00004607637,0.0001090654,0.0001574468,0.00009862941],"domain_scores_gemma":[0.9997801,0.00003778767,0.00006460201,0.00001139024,0.000050576,0.00005563398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008774816,0.00004698465,0.002548011,0.0001574968,0.00004550218,0.001096588,0.00008880105,0.0001484727,0.9853541,0.001008684,0.0008667886,0.007761185],"study_design_scores_gemma":[0.0002808445,0.0007151337,0.06440018,0.0001415532,0.0002707181,0.005052576,0.0007717208,0.006049254,0.8870323,0.001524363,0.03367109,0.00009023087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9207106,0.03810327,0.01973912,0.002191061,0.0008457104,0.0001363896,0.002240989,0.0004379639,0.01559496],"genre_scores_gemma":[0.9824652,0.003668565,0.005649322,0.0005681537,0.00006979954,0.0001101729,0.0008188696,0.0001029295,0.006546991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002041267,"threshold_uncertainty_score":0.006828785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004500067172763202,"score_gpt":0.2149395329870304,"score_spread":0.2104394658142672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}