{"id":"W2938129786","doi":"10.1038/s41467-019-09748-z","title":"PDGFRα+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research; Princess Margaret Cancer Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Cure Brain Cancer Foundation; Terry Fox Research Institute","keywords":"Progenitor cell; Biology; Stromal cell; Cell biology; Mesenchymal stem cell; Stem cell; Epithelium; Cellular differentiation; Mammary gland; Cancer research","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001298602,0.0001506892,0.0001107564,0.0004576589,0.0001260799,0.0002588116,0.00007823888,0.0001977306,0.0006442714],"category_scores_gemma":[0.00006356109,0.000193586,0.0001225385,0.00012192,0.0001407233,0.0001442713,0.0001560081,0.0003698781,0.0004017383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001498936,"about_ca_system_score_gemma":0.0001180767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004306392,"about_ca_topic_score_gemma":0.0006130508,"domain_scores_codex":[0.9999034,0.00001693913,0.000007666038,0.00002091674,0.00002753631,0.00002357134],"domain_scores_gemma":[0.99989,0.00001260564,0.00003187907,0.00001124761,0.00001076564,0.00004367066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001110371,0.00001427863,0.0007583335,0.00001106899,0.000001406547,0.00007070029,0.00002375091,0.00004796594,0.9978855,0.0001364213,0.00001650857,0.0009230991],"study_design_scores_gemma":[0.00001738316,0.0003245,0.01952623,0.0000107228,0.00001113246,0.0006169266,0.00009677746,0.0008893571,0.9756228,0.0001146197,0.002765145,0.000004397826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949579,0.001081012,0.002200722,0.00003779316,0.000008348422,0.00001932673,0.0003024391,0.00008436762,0.001308304],"genre_scores_gemma":[0.9936567,0.0005150941,0.001923123,0.00003589757,0.00000611925,0.00002561694,0.0002723194,0.00002840308,0.003536608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006442714,"threshold_uncertainty_score":0.002155304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009682936964389143,"score_gpt":0.269752352196757,"score_spread":0.2600694152323679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}