{"id":"W2938197061","doi":"10.1097/01.qai.0000557988.95699.8e","title":"I-102 Viral fitness costs and benefits of disrupting the host cell actin cytoskeleton in mucosal HIV-infection","year":2019,"lang":"en","type":"article","venue":"JAIDS Journal of Acquired Immune Deficiency Syndromes","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Biology; Context (archaeology); Cell biology; Cytoskeleton; Actin; Actin cytoskeleton; Chemokine receptor; Viral replication; Chemokine; Motility; Virology; Immunology; Cell; Virus; Inflammation; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001694673,0.0002280766,0.0002452331,0.000289003,0.0001623692,0.0005296955,0.0002375397,0.0004116002,0.002072305],"category_scores_gemma":[0.0003312066,0.0001211461,0.0001538238,0.000115226,0.0002272695,0.0003200507,0.0003068536,0.0005045908,0.0002158196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002958697,"about_ca_system_score_gemma":0.0001470821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004176604,"about_ca_topic_score_gemma":0.0007181146,"domain_scores_codex":[0.9998392,0.00004819378,0.000009882785,0.0000135278,0.00003840918,0.00005077046],"domain_scores_gemma":[0.9998054,0.00007026013,0.00002937934,0.00001654672,0.00001338719,0.00006515443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006463449,0.0001785171,0.003067376,0.00005155595,0.00001470448,0.0002524282,0.00001618939,0.0005057271,0.9868926,0.0006339435,0.00007186145,0.007668761],"study_design_scores_gemma":[0.0002594155,0.01007214,0.1989275,0.00008842311,0.0001753287,0.006602825,0.0008685857,0.01977567,0.7544703,0.002707493,0.005993873,0.00005849809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977749,0.0007793253,0.0001678751,0.00007544956,0.000007245495,0.000005034777,0.00005094356,0.000007005144,0.001132115],"genre_scores_gemma":[0.9985297,0.0003110779,0.0003711856,0.00002163825,0.00000825706,0.000006395036,0.00007810268,0.000006829107,0.0006669547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002072305,"threshold_uncertainty_score":0.006932557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01117394047484135,"score_gpt":0.2518895185999268,"score_spread":0.2407155781250855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}